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Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Minoxidil can reduce functions related to androgen receptors.

Chromosomal differences affect how muscle cells respond to testosterone.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

New steroids were effective in blocking male hormone receptors in hamster prostates.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Excess androgens may cause PCOS, not just be a symptom.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Antibody treatments show promise for hair loss but need more research.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

Androgens may block hair growth signals, targeting this could treat hair loss.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.