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Medications for PCOS don't seem to raise heart disease risk.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Mouse genital development depends on male or female hormones for specific features.

Muscles can make their own androgens, which may help muscle growth.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Adding hormone therapy to radiation improves survival for high-risk prostate cancer recurrence but has side effects.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Testosterone is crucial for development, growth, and various body functions in mammals.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Androgens may block hair growth signals, targeting this could treat hair loss.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Androgens prevent hair growth by changing Wnt signals in cells.