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30 / 1000+ resultsresearch 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line
This study demonstrates that DHT-induced lipid synthesis in sebocytes involves the mTOR pathway, suggesting mTOR inhibitors may help modulate androgen-dependent sebum overproduction.
research Relationship of androgens to female hirsutism and infertility.
This study observed that in cases of moderately severe male-pattern hirsutism, elevated free plasma androgen levels occur in 85% of patients, suggesting a subtle hyperandrogenic state as a common underlying factor.
research Alopecia and Hirsuties
The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
research Hirsutism, Male Pattern Baldness, and Acne in a 60-Year-Old Woman
Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.
research Updated Management of Atrophic Post Acne Scars: Review Article
This study concluded that combination therapies often yield better results for treating atrophic post-acne scars than single treatments.
research Hiperandrogenismo causado por tumor de células de Leydig de ovario
This case report describes a 65-year-old postmenopausal woman with hyperandrogenism caused by a non-malignant ovarian Leydig cell tumor, which is a rare cause of virilization.
research The Hair-An Syndrome: A Report of a Misdiagnosed Case with Unfortunate Outcome
This case report describes a misdiagnosed case of HAIR-AN syndrome with an unfortunate outcome, highlighting the challenges in distinguishing it from other hyperandrogenic conditions.
research Ectopic Adrenal Rests in Congenital Adrenal Hyperplasia as a Cause of Androgen Excess after Adrenalectomy Detected by Pelvic Venous Sampling
This case report describes an adult female with congenital adrenal hyperplasia who developed secondary amenorrhea and hair loss due to androgen overproduction from ovarian adrenal rests, detectable only after pelvic venous sampling, and normalizing after unilateral oophorectomy.
research Crystallization and preliminary X-ray analysis of the human androgen receptor ligand-binding domain with a coactivator-like peptide and selective androgen receptor modulators
This study reports the crystallization of the human androgen receptor's ligand-binding domain with nonsteroidal ligands, which may aid in understanding the differences in binding compared to steroidal ligands.
research Ovarian and Adrenal Androgens and Their Link to High Human Chorionic Gonadotropin Levels: A Prospective Controlled Study
In this study, women with a complete hydatidiform mole had significantly higher pre-evacuation levels of hCG, free testosterone, and DHEA-S compared to controls, which declined after HM evacuation.
research Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome
This study highlights the importance of understanding the roles of hyperandrogenemia and insulin resistance in the development and progression of PCOS, emphasizing further research to clarify their mutual influence.
research Androgen Conjugates: Physiology and Clinical Significance
This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.
research The Pathogenesis and Treatment Progress of Androgenic Alopecia
This research suggests that recent discoveries of signaling pathways in androgenic alopecia may pave the way for targeted therapies, providing potential new treatment options beyond the current FDA-approved drugs, minoxidil and finasteride.
research Leydig cell hyperplasia as a cause of virilization in a postmenopausal woman: A case report
This case study in a 62-year-old postmenopausal woman highlights Leydig cell hyperplasia as a likely cause of hyperandrogenism of ovarian origin, where bilateral oophorectomy resolved the condition and confirmed the diagnosis through histopathological examination.
research Women With Polycystic Ovary Syndrome: A Review of Susceptibility to Type 2 Diabetes
This review investigates the relationship between polycystic ovarian syndrome and the development of type 2 diabetes mellitus but reports no new clinical findings.
research Polycystic Ovary Syndrome in Adolescence
This article proposes a hypothesis that hyperandrogenemia is the final common pathway for developing adolescent PCOS and emphasizes the importance of reducing androgen levels to mitigate risks of metabolic syndrome, diabetes, and infertility in adulthood.
research Mister XX
This article discusses congenital adrenal hyperplasia due to 21 hydroxylase deficiency as a cause of ambiguous genitals in 46XX individuals and reports no new research findings.
research HPLC Profiling and Insilco studies of Chochurus olitoris (Jute) Leave Fractions against Steroid 5α-Reductase 2 (SRD5α2)
This review discusses the role of steroid 5 alpha reductase 2 in converting testosterone to DHT and its association with conditions like benign prostatic hyperplasia and prostate cancer; it reports no new results.
research The human skin as a hormone target and an endocrine gland
This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.
research Selected Disorders of Skin Appendages—Acne, Alopecia, Hyperhidrosis
This review discusses common skin appendage diseases, including their pathophysiology and treatments, but does not report new results.
research Hyperandrogenism in a postmenopausal woman: a rare case of ectopic adrenal cortical gland
This case report describes a 63-year-old woman with hyperandrogenism due to an ectopic adrenal gland adenoma on the ovaries, successfully treated with bilateral salpingo-oophorectomy.
research Testosterone: The Male Sex Hormone
This review outlines the role of testosterone in male sexual development and its therapeutic use for male hypogonadism, covering its biosynthesis, secretion, metabolism, and various biological actions, but does not report specific study results.
research Adrenal Cortex Tumors and Hyperplasias
This article reviews the types and characteristics of adrenal cortex tumors, including their hormone secretion and detection as incidental findings, but presents no new research results.
research Polycystic ovarian syndrome and associated hirsutism in the adolescent
This review discusses the unique challenges of diagnosing and managing polycystic ovarian syndrome in adolescents and reports no new clinical findings.
research Androgenic alopecia in post-menopausal female: a clinical presentation
This case study discussed a postmenopausal female with androgenic alopecia and hirsutism due to a Leydig cell tumor, suggesting the importance of further workup in women with severe hirsutism or androgenic alopecia.
research Medical treatment of male pattern alopecia (androgenic alopecia)
This review discusses potential causes of androgenic alopecia and explores treatment options, but provides no new clinical results; it emphasizes considering androgen overproduction syndromes in female patients.
research Dermatology of androgen-related disorders
This review discusses the dermatologic manifestations of hyperandrogenism in women and outlines the diagnostic approach and treatment options, reporting no new clinical results.
research Hepatic Adenoma in an Adolescent With Elevated Androgen Levels
This case report describes an adolescent girl with polycystic ovarian syndrome and endogenously elevated androgen levels who developed a hepatic adenoma, suggesting a link between the two conditions.
research Hidradenitis suppurativa: an-androgen-dependent disorder
Hidradenitis suppurativa improves with antiandrogen therapy.