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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.

Hormones and genes affect hair growth and male baldness.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.

A gene called BMAL1 plays a role in controlling hair growth.

Increased PPARGC1α relates to hair thinning in common baldness.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Exercise and finasteride together improve ovary health in PCOS rats.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.