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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

ERG increases SOX9, promoting prostate cancer growth and invasion.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Blocking testosterone speeds up wound healing in males.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Male hormones promote hair cell growth by using a growth factor from nearby skin cells.

High androgen levels in young women with PCOS are linked to higher blood pressure.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Too much androgen can cause hair loss; finasteride may help.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Lowering testosterone speeds up wound healing in male mice.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Spearmint tea may reduce testosterone and self-reported hair growth in women with PCOS.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

A new gene, JMJD1C, may affect testosterone levels in men.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.