May 2006 in “Women's Health Medicine” This review examines the causes, assessment, and treatments of hirsutism and highlights the need for future research in managing this condition but presents no new research findings.
March 2022 in “IntechOpen eBooks” This review discusses the complexities and co-morbidities associated with polycystic ovary syndrome, including its impact on metabolic and psychological health, and reports no new clinical results.
Hair loss in women can be caused by genetics, menopause, certain health conditions, and emotional stress, and it often results in thinner hair and a changing hairline.
January 2025 in “BMJ Case Reports” This case report describes a girl with familial adenomatous polyposis who exhibited heterosexual precocious puberty due to an adrenal tumor secreting cortisol and androgens; after her adrenalectomy, her hormone levels normalized and symptoms improved, illustrating the link between genetic syndromes and endocrine disorders.
This study evaluated an online survey tool designed to identify polycystic ovary syndrome, identifying areas for improvement that can aid in accurately assessing PCOS prevalence in general populations.
1744 citations
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August 2006 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.
253 citations
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March 2006 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.
3 citations
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April 2024 in “Molecular Human Reproduction” This study found that paxillin knockdown in human granulosa-derived cells and mouse models decreased androgen receptor protein levels and altered gene expression, suggesting paxillin's role in protecting against androgen excess effects, as observed in a polycystic ovary syndrome mouse model.
99 citations
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August 2003 in “Fertility and Sterility” This paper discusses polycystic ovary syndrome with a focus on androgen excess as the primary symptom and notes that insulin resistance may contribute to it in many patients, but provides no new research findings.
947 citations
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February 2004 in “The Journal of Clinical Endocrinology and Metabolism” In this study, polycystic ovary syndrome was the most prevalent cause of androgen excess, and suppressive hormonal therapy improved hirsutism, menstrual dysfunction, and acne in most patients, though side effects were common.
3 citations
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May 2025 in “Clinical Endocrinology” Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.
67 citations
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July 2006 in “Clinics in Dermatology” This review discusses the dermatologic manifestations of hyperandrogenism in women and outlines the diagnostic approach and treatment options, reporting no new clinical results.
46 citations
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July 1988 in “Journal of The American Academy of Dermatology” This review discusses various skin lesions associated with endocrinologic disorders such as Cushing's syndrome and adrenal insufficiency, and it reports no new clinical results.
151 citations
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December 2004 in “Annals of the New York Academy of Sciences” This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
10 citations
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March 2024 in “Endocrine Reviews” In this retrospective review, the author discusses key discoveries in understanding androgen excess disorders like PCOS, focusing on genetic and molecular insights gained from 1965 to 2015.
4 citations
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November 2019 in “Harper's Textbook of Pediatric Dermatology” This article reviews the skin, hair, nail, and mucosal changes linked to various pediatric endocrine disorders but provides no new clinical findings.
October 2025 in “Journal of the Endocrine Society” In this case report, the coexistence of hypercalcemia and androgen excess in a postmenopausal woman was linked to primary hyperparathyroidism and a suspected androgen-secreting ovarian tumor, underscoring the need for a comprehensive diagnostic approach to identify overlapping endocrine disorders.
June 2012 in “Springer eBooks” Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.
62 citations
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August 2018 in “Frontiers in Endocrinology” This review discusses the physiological roles of ovarian androgens in follicle development and atresia, emphasizing their contributions to polycystic ovary syndrome and normal follicle maturation but provides no new clinical results.
4 citations
,
January 2022 in “Open Health” This article discusses the challenges in treating PCOS, highlights the role of lifestyle interventions, and notes the lack of effective treatment beyond symptomatic management for this common reproductive health issue.
December 2022 in “International journal of preventive, curative & community medicine” This article reviews current understanding and management strategies for polycystic ovary syndrome, emphasizing lifestyle changes alongside medical treatment, and reports no new clinical results.
January 2021 in “ISGE series” This article discusses PCOS, highlighting its association with insulin resistance and chronic inflammation, and suggests that nutrition, exercise, and supplements may improve body composition and metabolic function, but reports no new clinical results.
October 2021 in “Journal of Advanced Biomedical and Pharmaceutical Sciences” This study reviews polycystic ovary syndrome and vitamin D, reporting no new results, and notes the involvement of vitamin D receptors and insulin in ovarian function.
March 2021 in “Serbian Journal of Experimental and Clinical Research” This review discusses hormonal and metabolic aspects of PCOS and highlights the need for more research to understand its pathophysiology, diagnosis, and treatment options; it reports no new results.
January 2019 in “ISGE series” This review discusses the criteria, diagnosis, and treatment options for polycystic ovary syndrome and reports no new clinical results; it highlights the need for further research on causative treatments.
March 2026 in “Cleveland Clinic Journal of Medicine” This review discusses polycystic ovary syndrome and incorporates updates from a 2023 guideline, but reports no new research findings on diagnosis or management.
16 citations
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January 2023 in “Cureus” This article discusses the characteristics and potential consequences of polycystic ovarian syndrome, including its effects on fertility and risk for other health conditions, but it reports no new findings.
July 2023 in “CRC Press eBooks” This chapter reviews various ayurvedic formulations for managing PCOS symptoms but presents no new research findings, suggesting further detailed exploration of their efficacy through an ayurvedic perspective.
December 2016 in “Asian Pacific journal of cancer biology” This paper discusses the importance of early diagnosis and treatment of polycystic ovarian syndrome to potentially reduce long-term complications like diabetes, hypertension, and heart disease, but reports no new clinical outcomes.
August 2008 in “Obstetrics & gynecology science” This review discusses the various features, diagnostic challenges, and associated immediate and long-term morbidities of polycystic ovary syndrome, highlighting its significant impact on quality of life and costs, but reports no new clinical results.