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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

DHT stops hair regrowth in mice, similar to human hair loss.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.