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Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Too much androgen can cause hair loss; finasteride may help.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Prolactin may be important for skin growth and immune function.

Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.