research The Case of the Elusive Androgen
The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
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research Women With Clinically Significant Hirsutism Always Have Detectable Endocrinological Abnormalities
All women with significant unwanted hair growth have hormonal imbalances, often from polycystic ovary syndrome.
research Increased Frequency of Heterozygosity for 21-Hydroxylase Deficiency Among Hirsute Females
Women with excessive hair growth or polycystic ovary disease may more often carry a gene variant for 21 hydroxylase deficiency.
research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research The Acne Hormones
Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Insulin Resistance and Polycystic Ovary Syndrome
Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
research Women With Clinically Significant Hirsutism Always Have Detectable Endocrinological Abnormalities
Most women with excessive hair growth have a hormonal cause.
research Measurement and Comparison of Various Androgen Levels in Women with Severe Acne, Hirsutism, and Androgenic Alopecia
Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
research Relationship Between Plasma Sex Hormones and Severity of Coronary Artery Disease
Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.
research Female Pattern Hair Loss
Female pattern hair loss affects crown, increases with age, and has limited treatments.
research Androgenetic Alopecia
Minoxidil was promising for treating male and female pattern baldness in 1994, but more research on genetics and other treatments was needed.
research Structural Perspectives on the Androgen Receptor, the Elusive Shape-Shifter
The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research Pharmacology of Anti-Androgens in the Skin
Anti-androgens can help reduce the effects of male hormones on the skin.
research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
research The Enzyme and Inhibitors of 4-Ene-3-Oxosteroid 5α-Oxidoreductase
Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.
research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research A Randomized Placebo-Controlled Study on the Effects of Pioglitazone on Cortisol Metabolism in Polycystic Ovary Syndrome
Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
research Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells
Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts
Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research A New Target for Squamous Cell Skin Cancer?
Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
research Effect of the Multifunctional Cosmetic Ingredient Sphinganine on Hair Loss in Men and Women with Diffuse Hair Reduction
Sphinganine can reduce hair loss and improve scalp health.
research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse
Disrupted stem cell signals in hairpoor mice cause hair loss.
research Diseases Of The Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.