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This study found that a data-driven model using XGBoost effectively predicts individualized responses to minoxidil for androgenetic alopecia, outperforming traditional methods in accuracy and reliability.

This study identified 12 potential candidate biomarkers associated with hair loss by analyzing the differential expression of genes, suggesting possible therapeutic targets for alopecia.

This study developed a straightforward HPTLC method for detecting nicotine and cotinine in human plasma and urine, concluding that liquid-liquid extraction with methanol: chloroform: ammonia achieved optimal separation and is applicable for forensic analysis of lethal nicotine intoxication.

This study found that two eco-friendly analytical methods for quantifying Finasteride and Tadalafil in a new dosage form were effective, green, and suitable for quality control.

In this study, a bidirectional Mendelian randomization analysis found a causal link between alopecia areata and hypothyroidism, indicating that each condition may influence the other, while no similar relationship was observed between androgenetic alopecia and hypothyroidism.

This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.

This study found that LC-MS/MS assays provided more reliable and precise steroid measurements in human serum compared to traditional immunoassays, particularly at lower concentrations.

This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.

In this study, researchers used SEM/SDD-EDS to identify waterborne minerals like calcium and aluminum in the scalp hair cuticle of individuals using treated or untreated water for hair washing, finding that prior application of coconut oil or conditioners can prevent calcium uptake.

This study suggests potential bidirectional causal links between certain sleep traits, like insomnia and reduced sleep duration, and types of alopecia, including alopecia areata; however, these associations did not hold after correcting for multiple tests, warranting cautious interpretation.

Current evidence reviewed in this study indicates that finasteride, a drug for hair loss, can cause depression and suicidality, with delayed recognition partly due to insufficient post-approval pharmacovigilance by manufacturers and regulators.

This study found that 10.3% of female high school students in Islamabad screened positive for PCOS, with associations including irregular menstrual cycles and higher BMI among those testing positive.

In this Mendelian randomization study, shortened leukocyte telomere length was associated with an increased risk of androgenetic alopecia, but no causal relationship was found with alopecia areata.

This study found that oral minoxidil is associated with a higher proportional reporting of several cardiovascular adverse events compared to topical minoxidil in spontaneous FDA reports, but these signals should be interpreted as hypothesis-generating rather than evidence of clinical safety.

This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.

This study found significant gender-based differences in forehead dimensions among 297 participants, with males showing larger vertical measurements, which could inform applications in forensic identification, cosmetic surgery, and anthropological research.

This study explored how alopecia impacts the socio-emotional lives and daily adaptation of women, finding that while not life-threatening, alopecia initially affects how they adjust to daily routines and perceive social and partner relationships.

This study developed and validated a method for measuring stress biomarkers in hair during pregnancy, finding that glucocorticoid levels increased over trimesters while endocannabinoid levels remained constant, suggesting hair analysis as a reliable tool for monitoring stress responses in pregnant women.

The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.

The method effectively maps lead and zinc in hair, aiding understanding of heavy metal exposure risks.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

This study found that a new analytical approach revealed an increased brain pregnenolone level following finasteride treatment in a mouse model, suggesting potential for improved understanding of neurosteroid roles in brain excitability.

This study found that age-related fluctuations in hormones and endocannabinoids in male C57BL/6 mice showed specific patterns, with peak values observed around 2.7 to 3.4 months, with these patterns seen in both plasma and hair but with different magnitudes.

In this study, silver oxide-based nanoparticles were used to ionize analytes and detect specific target molecules through adduct formation with silver isotopes, facilitating signal correlation with these molecules.

This study found that ATR-FTIR spectroscopy combined with machine learning effectively differentiated alopecia areata patients from healthy controls with an AUC of 0.85, and also showed promise in predicting treatment response, particularly through alterations in the Amide I band.

Homemade hair treatments can significantly lower drug levels in hair, possibly causing false-negative drug tests.

This review outlines a diagnostic approach for identifying non-PCOS pathology in women with androgen excess, emphasizing the importance of clinical history and biochemical phenotyping but reports no new clinical results.

This study found that progesterone levels were higher and increased significantly throughout pregnancy, contrasting with stable levels in non-pregnant women.

This study observed that pelage development in male blue foxes born in early June was more synchronized than those born in early May, with differences likely influenced by melatonin levels.