72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
77 citations,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
March 2011 in “Journal of clinical and experimental investigations” Thallium poisoning can cause hair loss, skin rashes, and nerve damage, and can be fatal if not correctly diagnosed and treated.
236 citations,
January 1951 in “Physiological zoology” Hair growth and pigmentation in mice involve specific stages crucial for research.
29 citations,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
127 citations,
December 2007 in “Journal of Investigative Dermatology” Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
112 citations,
July 1998 in “Journal of Investigative Dermatology” Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
91 citations,
May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
23 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
17 citations,
May 2010 in “Journal of Dermatological Science” Erythropoietin helps hair grow and could be a potential treatment for hair loss.
16 citations,
April 2015 in “Lasers in Surgery and Medicine” Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
13 citations,
July 2016 in “BMC Complementary and Alternative Medicine” Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.
10 citations,
January 2016 in “PLOS ONE” Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
7 citations,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
October 2021 in “Research Square (Research Square)” Melatonin affects certain genes and pathways involved in cashmere goat hair growth.
June 2021 in “Research Square (Research Square)” Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
60 citations,
October 2005 in “Experimental Dermatology” Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.
27 citations,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
17 citations,
May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
6 citations,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Gray hair regained color after thyroid hormone treatment.
188 citations,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
30 citations,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
22 citations,
April 2017 in “Journal of Investigative Dermatology” Non-coding RNAs are crucial for skin development and health.
16 citations,
September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
New insights into cell communication in psoriasis suggest innovative drug treatments.