15 citations
,
March 2014 in “Molecular Medicine Reports” This study found that α-spinasterol treatment significantly reduced testosterone propionate-induced prostatic hyperplasia in rats, suggesting potential benefits for managing benign prostatic hyperplasia.
13 citations
,
August 1995 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that the pH dependency of rat steroid 5α-reductase type II isozyme significantly affects its kinetic properties, including Vmax and Km, suggesting past discrepancies in literature may arise from these pH variances during assays.
12 citations
,
April 2020 in “Facial Plastic Surgery Clinics of North America” This article discusses potential complications in hair restoration surgery and emphasizes the importance of thorough planning and patient participation in reducing risks, but reports no new clinical findings.
12 citations
,
October 2004 in “Experimental Gerontology” This review summarizes how common polymorphisms in androgen and estrogen receptor genes may influence aging-related symptoms and diseases in men, but it reports no new clinical results.
11 citations
,
August 1997 in “Expert Opinion on Therapeutic Patents” This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.
10 citations
,
May 2010 in “Analytica Chimica Acta” This study reported the development of two highly sensitive ELISA assays to detect banned substances finasteride and dutasteride in human urine, offering better sensitivity than existing HPLC/MS/MS methods.
10 citations
,
April 2000 in “Archives of Oral Biology” Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
8 citations
,
June 2016 in “Journal of Pharmacy Practice” This case report suggests that lisinopril may cause alopecia, which resolved after the patient switched to losartan potassium.
8 citations
,
September 2008 in “Medical Hypotheses” This article proposes a novel hypothesis that androgenetic alopecia may be mainly caused by skull bone expansion affecting blood supply to hair follicles rather than differences in individual follicle programming, and calls for more genetic research into skull development.
7 citations
,
July 2019 in “Scientific Reports” In this study, anti-androgenic therapy with finasteride for prostate disease was associated with reduced cardiac hypertrophy in heart failure patients, encouraging further investigation in larger cohorts.
7 citations
,
August 2018 in “Journal of Cosmetic and Laser Therapy” This study proposes an innovative treatment for stretch marks by combining skinbooster and microneedling techniques, which induce tissue remodeling and collagen synthesis, and suggests using confocal microscopy as a valuable tool for monitoring skin changes in aesthetic dermatology.
7 citations
,
January 1992 in “Adolescent and pediatric gynecology” This review discusses the unique challenges of diagnosing and managing polycystic ovarian syndrome in adolescents and reports no new clinical findings.
5 citations
,
December 2021 in “Physiological Research” This paper reviews the role of androgens in SARS-CoV-2 infection and their potential impact on disease severity, suggesting androgen-targeting strategies might influence outcomes, but reports no new clinical results.
5 citations
,
March 2015 in “Women's Health” This article reviews the process for diagnosing polycystic ovary syndrome and suggests how it can be applied in clinical practice but reports no new results.
5 citations
,
June 2014 in “Gastroenterology report” This report describes a case of colonic adenomatous polyposis in a patient with Cronkhite-Canada syndrome, highlighting a deviation from the typically hamartomatous polyps and suggesting a need for further study.
4 citations
,
March 2021 in “Case Reports” In this case study, a 71-year-old woman with postmenopausal hirsutism was diagnosed with a Leydig cell tumor and endometrial carcinoma, with hirsutism improving one month after surgery.
4 citations
,
May 2019 in “Zeitschrift für Naturforschung C” This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.
4 citations
,
October 1988 in “Clinics in Dermatology” This paper reviews current knowledge about androgens' role in androgenic alopecia and female hirsutism but presents no new clinical findings.
3 citations
,
November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
3 citations
,
June 1983 in “Archives of Dermatology” This article discusses the effectiveness of adrenal cortex compounds E and F in treating connective tissue disorders like rheumatoid arthritis and lupus erythematosus, but it reports no new clinical results.
2 citations
,
December 2024 in “Iraqi Journal of Laser” This study used enhanced Raman spectroscopy to successfully detect ultra-low levels of free testosterone in women with PCOS, suggesting a potential low-cost method for early diagnosis.
2 citations
,
January 2012 in “Journal of metabolic syndrome” This review summarizes current knowledge on the diagnosis and treatment of hirsutism but provides no new clinical results.
1 citations
,
March 2021 in “The Journal of Sexual Medicine” This study reported that testosterone replacement therapy was not linked to worse COVID-19 outcomes in men, though the data showed high hospitalization and fatality rates that suggest otherwise.
1 citations
,
March 2018 in “Dermatologie pro praxi” This article reviews over-the-counter products and active ingredients marketed for hair loss treatment, noting that many lack robust efficacy evidence except for minoxidil, which has temporary effects, and highlights the caution needed when recommending products to pregnant and breastfeeding women.
1 citations
,
January 2015 in “Journal of clinical and investigative dermatology” This study suggests that IGF-1, a component of human placenta hydrolysate, promotes hair growth by increasing the number and size of hair follicles in mice.
1 citations
,
August 2012 in “Journal der Deutschen Dermatologischen Gesellschaft” A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.
March 2026 in “Canadian Urological Association Journal” This study observed that complementary and alternative medicine, often marketed to men as ways to enhance "optimization," "recovery," and "vitality," has become mainstream, with many believing in its benefits for testosterone, erections, libido, hair loss, and sperm quality.
March 2026 in “Frontiers in Pharmacology” This study reviews new treatments for androgenetic alopecia, including cell-derived exosomes and investigational drugs, which show potential to improve hair density and quality but require more rigorous and standardized trials to confirm efficacy and safety.
January 2026 in “Revista Científica de la Facultad de Ciencias Veterinarias” This study concluded that both ozonated oil and Centella asiatica extract effectively accelerated wound healing in mice through different mechanisms, with the former enhancing early-stage inflammation and the latter promoting collagen deposition and regenerative healing.
December 2025 in “International Journal of Pharmacology” This review highlights that iPSC-derived artificial platelets offer a promising alternative to platelet-rich plasma for regenerative medicine, with standardized manufacturing and reproducible pharmacological properties, addressing variability issues associated with donor-derived platelets and showing therapeutic potential in preclinical models of osteoarthritis.