research Steroid 5α-Reductases and 3α-Hydroxysteroid Dehydrogenases: Key Enzymes in Androgen Metabolism
Key enzymes control androgen levels, affecting hormone activity and potential treatments.
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research Hair Loss (Alopecia or Baldness)
Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
research Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products
Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
research A Role for Steroid 5 Alpha-Reductase 1 in Vascular Remodeling During Endometrial Decidualization
The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
research Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
Pumpkin seed oil helps hair growth in men with hair loss.
research Prolonged Use of Finasteride-Induced Gonadal Sex Steroids Alterations, DNA Damage, and Menstrual Bleeding in Women
Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
research Obstetric Dermatology
The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
research Testosterone Hormone: Clinical Indications, Dysregulation, and Therapeutic Methods
Testosterone is vital for male health, and its deficiency is linked to aging and common health issues.
research Osteoanabolic Estrogen Therapy in a Transsexual Man
Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.
research Effects of the Anti-Androgen Finasteride on 5-Alpha-Reductase Activity in Human Gingival Fibroblasts in Response to Minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
research No Evidence That 2D:4D Is Related to the Number of CAG Repeats in the Androgen Receptor Gene
Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
research The Effect of Minocycline on the Metabolism of Androgens by Human Oral Periosteal Fibroblasts and Its Inhibition by Finasteride
Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
research Early-Onset Androgenetic Alopecia and Endocrine Disruptors
Endocrine disruptors may cause early hair loss.
research Androgenetic Alopecia: Clinical Features, Classification, and Treatments
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells
Androgens slow hair growth by altering Wnt signaling in balding cells.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research Guidelines of Care for Androgenetic Alopecia
Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.
research Current Issues on the Genetic Implications and Treatment of Androgenic Alopecia
Hair loss is linked to heart disease and metabolic syndrome, and while current treatments vary in effectiveness, more research is needed for better solutions.
research Assessment of Semen Quality in Patients with Androgenetic Alopecia in an Infertility Clinic
Men with severe hair loss may have poorer sperm quality.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Discovery of Nonsteroidal Androgens
Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
research 3 Alpha, 17 Beta-Androstanediol Glucuronide in Plasma: A Marker of Androgen Action in Idiopathic Hirsutism
High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.
research The Effectiveness of Adding Low-Level Light Therapy to Minoxidil 5% Solution in the Treatment of Patients with Androgenetic Alopecia
Adding low-level light therapy to minoxidil improves hair growth and patient satisfaction.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research High Circulating Estrone and Low Testosterone Correlate with Adverse Clinical Outcomes in Men with Advanced Liver Disease
Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
research Short- and Long-Term Clinical Skin Effects of Testosterone Treatment in Trans Men
Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
research Diffuse Hair Loss: Causes, Diagnosis, and Treatment
Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
research Drugs and Hair Loss: Mechanisms and Clinical Implications
Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.