Early-Onset Androgenetic Alopecia and Endocrine Disruptors

January 2011 in “ Journal of biological research ”

Marcella Guarrera, M.C. Fiorucci

androgenetic alopecia endocrine disruptors androgen hormones genetic predisposition environmental exposure alimentary exposure cosmetic overexposure sexual hormones exogenous substances hormone synthesis hormone secretion hormone transport hormone binding hormone action hormone elimination AGA EDs

TLDR Endocrine disruptors may cause early hair loss.

This paper discusses the link between early-onset androgenetic alopecia (AGA) and endocrine disruptors (EDs). AGA is a common type of hair loss caused by androgen hormones in individuals with a genetic predisposition. While AGA typically starts after puberty, it has been observed in adolescents, with a slight prevalence in males. The premature onset of AGA may be caused by environmental, alimentary, or cosmetic overexposure to sexual hormones or EDs. EDs are exogenous substances that interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body, causing adverse effects to human health. The paper suggests that EDs may play a role in the pathogenesis of early-onset AGA.

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