Early-Onset Androgenetic Alopecia and Endocrine Disruptors
January 2011
in “
Journal of biological research
”
Studysummary This review discusses potential links between early-onset androgenetic alopecia and exposure to endocrine disruptors in adolescents, but reports no clinical results; the authors suggest further investigation.
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This paper discusses the link between early-onset androgenetic alopecia (AGA) and endocrine disruptors (EDs). AGA is a common type of hair loss caused by androgen hormones in individuals with a genetic predisposition. While AGA typically starts after puberty, it has been observed in adolescents, with a slight prevalence in males. The premature onset of AGA may be caused by environmental, alimentary, or cosmetic overexposure to sexual hormones or EDs. EDs are exogenous substances that interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body, causing adverse effects to human health. The paper suggests that EDs may play a role in the pathogenesis of early-onset AGA.