Early-Onset Androgenetic Alopecia and Endocrine Disruptors

January 2011 in “ Journal of biological research ”

Marcella Guarrera, M.C. Fiorucci

androgenetic alopecia endocrine disruptors androgen hormones genetic predisposition environmental exposure alimentary exposure cosmetic overexposure sexual hormones exogenous substances hormone synthesis hormone secretion hormone transport hormone binding hormone action hormone elimination AGA EDs

TLDR Endocrine disruptors may cause early hair loss.

This paper discusses the link between early-onset androgenetic alopecia (AGA) and endocrine disruptors (EDs). AGA is a common type of hair loss caused by androgen hormones in individuals with a genetic predisposition. While AGA typically starts after puberty, it has been observed in adolescents, with a slight prevalence in males. The premature onset of AGA may be caused by environmental, alimentary, or cosmetic overexposure to sexual hormones or EDs. EDs are exogenous substances that interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body, causing adverse effects to human health. The paper suggests that EDs may play a role in the pathogenesis of early-onset AGA.

View this study on pagepressjournals.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 2 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Anyone else growing tired of the finasteride wars?

in Finasteride/Dutasteride 169 upvotes 1 year ago

The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

community Why balding gets worse in every generation?

in Chat 81 upvotes 6 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community Is it me or are people losing their hair very young now?

in Finasteride/Dutasteride 143 upvotes 4 years ago

People notice more young individuals experiencing hair loss and discuss possible reasons, such as diet, hormones, and stress. Some treatments mentioned include finasteride, dutasteride, and minoxidil.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 729 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 1 year ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

Related Research

2 / 2 results

A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors

research A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors

30 citations, December 2017 in “Medical Hypotheses”

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

research Pharmacological Basis for Clinical Use of Antiandrogens

24 citations, July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.