research In Search of New Therapeutics: Molecular Aspects of the PCOS Pathophysiology - Genetics, Hormones, Metabolism and Beyond
New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
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570-600 / 760 resultsresearch 3 Alpha, 17 Beta-Androstanediol Glucuronide in Plasma: A Marker of Androgen Action in Idiopathic Hirsutism
High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Blinded, Randomized, Quantitative Grading Comparison of Minimally Invasive, Fractional Radiofrequency and Surgical Face-Lift to Treat Skin Laxity
Surgical face-lifts are more effective, but fractional radiofrequency is a good, less invasive alternative for treating skin laxity.
research Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators
Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
research Equine Epidermis: A Source of Epithelial-Like Stem/Progenitor Cells with In Vitro and In Vivo Regenerative Capacities
Horse skin stem cells combined with platelet-rich plasma improve skin healing.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research The Good, the Bad, and the Ugly Facets of Insulin Resistance
Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
research Reporting in Clinical Studies on Platelet-Rich Plasma Therapy Among All Medical Specialties: A Systematic Review of Level I and II Studies
The review concluded that reporting on PRP therapy is often incomplete, leading to uncertainty about its effectiveness.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research The Possible Role of Prescribing Medications in Contributing to Male-Factor Infertility: Assessment of the FDA Pharmacovigilance Database
Some medications might contribute to male infertility, with finasteride showing a high number of reports.
research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
research Virilizing Adrenocortical Oncocytoma in a Toddler
A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.
research The Impact of Levothyroxine on Thyroid Autoimmunity and Hypothalamic–Pituitary–Thyroid Axis Activity in Men with Autoimmune Hypothyroidism and Early-Onset Androgenetic Alopecia
Levothyroxine is less effective in men with early-onset male-pattern baldness.
research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
research Sex Chromosome Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Cushing's Syndrome Complicating Pemphigoid Gestationis
Careful management of steroid use is crucial in pregnant women with bullous pemphigoid to avoid complications like Cushing syndrome.
research Impaired Prolactin-Lowering Effects of Metformin in Women with Polycystic Ovary Syndrome
Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.
research Metabolic Syndrome and Skin Diseases
Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
research Reporting on Adverse Clinical Events
Different medications can cause serious side effects in some people.
research Applications of Steroid Drugs Entrapped in Cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Androgen Replacement Therapy in Women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
research An Attempt to Assess the Magnitude of Endogenous Androgen Production in a Case of the Adrenogenital Syndrome
A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
research Microbial Oxidation of Finasteride with Macrophomina Phaseolina (KUCC 730)
research Index
research The Investigation of Insulin Resistance and Metabolic Syndrome in Male Patients with Early-Onset Androgenetic Alopecia
Early balding men may have insulin resistance, but lifestyle changes can help.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.