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This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.

This study found that bolandiol increased lean body mass and bone mineral density in castrate adult male rats, exhibiting tissue selectivity and acting through multiple receptor pathways with less potency compared to other androgens.

This study suggests that the testosterone analogs 7α-Methyltestosterone and 7α-Ethyltestosterone may offer promising androgenic, progestogenic, and anabolic properties for development as male contraceptives.

This study synthesized nonsteroidal ligands as second-generation androgen receptor agonists and identified three compounds with significant anabolic activity and moderate to minimal androgenic activity in vivo.

This review critically evaluates the evidence for SARMs' tissue selectivity and suggests their clinical benefits over traditional androgens are not yet well-supported by robust evidence, underscoring the need for further head-to-head trials.

In this review, the authors highlight that drugs promoting androgenic activity or inhibiting estrogenic activity may unmask or worsen androgenetic alopecia in genetically predisposed individuals, indicating the need for careful management in clinical settings.

In this study, finasteride was found to worsen the cardiac effects but reduce the mutagenic effects of nandrolone in male Wistar rats.

This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.

This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.

In this study, finasteride increased cardiac damage but reduced mutagenic effects in male rats treated with anabolic steroid ND, suggesting variable organ-specific responses to metabolic inhibition.

This review discusses hormones that affect acne and highlights a statistically significant link between a low-glycemic-load diet and reduced acne activity, but reports no new experimental findings.

This case report examines the long-term impact of extensive anabolic-androgenic steroid use on metabolic and cardiovascular health, highlighting adverse effects to guide primary care for this patient group.

This review found that hormones significantly impact women's health and athletic performance, influencing the menstrual cycle, menopause, and exercise responses, while therapies like contraception and hormone replacement require personalized approaches to balance benefits and risks.

This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.

This article reviews the development of selective androgen receptor modulators and myostatin inhibitors as performance-enhancing drugs, highlighting ongoing challenges in achieving truly tissue-selective anabolic agents and reporting no new experimental findings.

This review highlights the various nonmedical uses of anabolic androgenic steroids and associated polypharmacy, suggesting that preventing their abuse should be a public health priority, but it reports no new findings.

This paper proposes a theory explaining how the normal anabolic effects of androgens lead to structural changes and hair follicle miniaturization, contributing to androgenic alopecia.

This source reports that while creatine supplementation is popular for improving muscle mass and performance, questions about its efficacy and safety persist. An expert team is reviewing literature to address concerns like water retention, renal effects, and its benefits across different populations and uses.

This article reviews recent advances in the synthesis of oxasteroids and reports no new experimental results.

This chapter reviews selective androgen receptor modulators, discussing their therapeutic potential beyond current androgen applications, and reports no new clinical findings.

This study found that dihydrotestosterone (DHT) suppresses prostaglandin E2 and TGF-β induced IGF-I gene promoter activity in osteoblasts, suggesting complex interactions among bone growth regulators and potential complications from anabolic steroid use.

This review suggests that brassinosteroids may have similar biological activities in both plants and other organisms, prompting further exploration of steroid regulation mechanisms across different life forms.

This study by Gao et al. reports that two nonsteroidal selective androgen receptor modulators, S1 and S4, demonstrated tissue-selective actions in rats, suppressing prostate growth while maintaining muscle growth without altering hormone levels.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

In this study, researchers found that taking Saw palmetto and Pygeum africana supplements for five days altered the urinary steroid profile in a way that may interfere with the steroidal module of the Athlete Biological Passport.

This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.

This study identified novel selective androgen receptor modulators with enhanced in vivo pharmacological activity through structure-activity relationship analysis in castrated rats.

This review discusses the cardiovascular risks associated with anabolic-androgenic steroid use and reports that, despite known toxic effects, further research is needed to clarify the causality of these risks.

This article reviews the skin effects of anabolic-androgenic steroid use in athletes but reports no clinical results.

This case study potentially links the use of anabolic steroids to increased severity of COVID-19 in a healthy 28-year-old man, with marked symptom improvement following treatment with proxalutamide.