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The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

OsUEV1B protein is essential for controlling phosphate levels in rice.

Sonic hedgehog proteins may help grow hair.

CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.

Inherited color dilution in Rex rabbits is linked to DNA methylation changes in hair follicles.

Understanding skin structure and development helps diagnose and treat skin disorders.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Hair loss needs more research for better treatments.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.