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The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Older age, pre-existing skin conditions, cirrhosis, and pegylated interferon use increase the risk of skin issues during hepatitis C treatment.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

Dutasteride effectively and safely treats male hair loss for over a year.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

5-Alpha-Reductase inhibitors shorten COVID-19 recovery time in men.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Oral pulse steroids reduce TNF-α levels, improving alopecia areata.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.

EPC-K is stable except at very acidic pH or when exposed to sunlight, and it can decompose in low ethanol concentrations.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Finasteride may affect PNMT, causing side effects.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.