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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Finasteride may affect PNMT, causing side effects.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

Anti-TNF therapy can cause hair loss and skin issues.

Sp6 promotes tooth development by reducing follistatin levels.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

The powder shampoo with cinnamon extract has strong antioxidant properties and is eco-friendly.

Pumpkin roots contain compounds like Alpha-spinasterol, squalene, and palmitic acid, which may have health benefits like reducing depression, treating certain cancers, and having antibacterial properties.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Bimatoprost, a glaucoma medication, may also help treat hair loss.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.