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    Glossary Alopecia Areata

    autoimmune disorder causing patchy hair loss on scalp and body

    Alopecia Areata (AA) is an autoimmune condition where the body's immune system mistakenly attacks hair follicles, leading to patchy hair loss on the scalp and other areas of the body. This condition can affect individuals of all ages and often results in round, smooth bald patches, though the extent and pattern of hair loss can vary widely.

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    1. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity Nature · 2010 · 717 citations
    2. Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition Nature medicine · 2014 · 701 citations
    3. Alopecia Areata The New England Journal of Medicine · 2012 · 421 citations
    4. Alopecia areata update Journal of The American Academy of Dermatology · 2010 · 391 citations
    5. Familial aggregation of alopecia areata Journal of the American Academy of Dermatology · 2016 · 295 citations
    6. Alopecia Areata: an Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021 · 290 citations
    7. Alopecia areata Journal of The American Academy of Dermatology · 2017 · 290 citations
    8. Lymphocytes, neuropeptides, and genes involved in alopecia areata Journal of Clinical Investigation · 2007 · 286 citations
    9. The pattern and profile of alopecia areata in Singapore – a study of 219 Asians International Journal of Dermatology · 2002 · 275 citations
    10. Alopecia areata update Journal of the American Academy of Dermatology · 2010 · 244 citations
    11. Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients Journal of The American Academy of Dermatology · 2016 · 238 citations
    12. Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b–3 trial The Lancet · 2023 · 227 citations
    13. Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata JCI insight · 2016 · 222 citations
    14. British Association of Dermatologists’ guidelines for the management of alopecia areata 2012 British Journal of Dermatology · 2012 · 218 citations
    15. A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata British Journal of Dermatology · 2013 · 205 citations
    16. Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata JCI insight · 2016 · 196 citations
    17. Clinical significance of dermoscopy in alopecia areata: analysis of 300 cases International Journal of Dermatology · 2008 · 196 citations
    18. Alopecia areata: a review of disease pathogenesis 2018 · 191 citations
    19. Alopecia Areata: A tissue specific autoimmune disease of the hair follicle Autoimmunity Reviews · 2005 · 185 citations
    20. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015 · 184 citations
    21. Alopecia areata Journal of the American Academy of Dermatology · 2017 · 182 citations
    22. Guidelines for the management of alopecia areata British Journal of Dermatology · 2003 · 182 citations
    23. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994 · 178 citations
    24. Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing 2015 · 176 citations
    25. Interventions for alopecia areata Cochrane library · 2008 · 164 citations
    26. Juvenile versus maturity-onset alopecia areata- a comparative retrospective clinical study Clinical and Experimental Dermatology · 1989 · 164 citations
    27. The autoimmune basis of alopecia areata: A comprehensive review Autoimmunity reviews · 2014 · 162 citations
    28. PROFILE OF ALOPECIA AREATA: A QUESTIONNAIRE ANALYSIS OF PATIENT AND FAMILY International Journal of Dermatology · 1992 · 161 citations
    29. Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA) Journal of the American Academy of Dermatology · 2015 · 157 citations
    30. Alopecia areata International Journal of Dermatology · 2007 · 151 citations