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This review summarizes the structural and chemical characteristics of current and novel antiandrogenic drugs but reports no new clinical findings.

This study suggests that activating the PPARs/SHH-mitochondrial axis may enhance diabetic wound healing by improving endothelial cell metabolism and angiogenesis, indicating potential for PPAR agonists in treating diabetic foot ulcers.

TLR7-based compounds may help manage chemotherapy-induced hair loss.

This study by Dr. Manka and colleagues reported that thyroid hormones play a significant role in regulating hepatic stellate cells, influencing liver fibrosis progression via TGFβ signaling. They found that TRα signaling might enhance scar-free tissue regeneration, offering potential pathways for targeted liver fibrosis treatments.

This article discusses the various roles of steroids in vertebrate organ systems and notes several glucocorticoids that were among the Top 200 Drugs by sales in the 2010s, but it reports no new clinical findings.

This article reviews the causes and treatments of hypertrichosis and hirsutism and reports no new clinical findings; the authors compare diagnostic strategies and discuss available treatment options.

This study reports that AhR pathway expression is significantly reduced in lymphocytes of alopecia areata patients, suggesting its potential as a diagnostic marker and therapeutic target.

This study suggests that persistent symptoms in patients with controlled functioning adenomas may indicate a coexisting PCOS diagnosis, highlighting the need for precise differentiation and timely management of these conditions.

Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.

This article reviews the physiology, causes, and treatments of hirsutism and reports no new research findings.

This review summarizes current knowledge on the diagnosis and treatment of hirsutism but provides no new clinical results.

This review highlights that while lifestyle changes may help with many ovulatory disorders, oocyte donation is considered a viable option for patients who cannot undergo ovulation induction; it reports no new results.

This review discusses how dysfunction in keratinocyte adhesion affects skin integrity and conditions like alopecia and keratoderma, highlighting the roles of intercellular junctions, and reports no new clinical results.

This study suggests that targeting adenosine receptors could be an effective strategy for reducing inflammation in inflammatory skin disorders, with promising results observed in animal models.

This review discusses various diagnostic and treatment strategies for canine prostate diseases, including pharmacological options and advanced procedures, but reports no new clinical results.

In this study, researchers found that activating the delta opioid receptor with a specific agonist significantly promoted hair growth in mice, suggesting potential for developing new hair-loss treatments.

This review explores the current treatments for different types of alopecia, emphasizing the need for well-designed clinical trials and highlighting that most therapies are used off-label, as only androgenetic alopecia has FDA-approved drugs.

This article reports two cases where ovarian hyperthecosis caused hyperandrogenism in postmenopausal women, confirmed by imaging and resolved after bilateral oophorectomy.

This review explores the therapeutic applications of bimatoprost, including its role in glaucoma treatment, hair growth stimulation, and potential effects on fat deposition, but reports no new experimental findings.

This chapter discusses common endocrine disorders affecting the pituitary, thyroid, and adrenal glands, and their impact on human fertility, emphasizing practical evaluation and treatment algorithms.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

This article discusses pharmacologic treatments for male sexual offenders, focusing on reducing sexual drive through nonhormonal or hormonal means, but it reports no new clinical results.

In this study, researchers developed and tested a novel peptide, AMHR2BP, which mimics the function of Anti-Müllerian hormone to protect ovarian follicles in mice, showing promise for preserving ovarian health during chemotherapy without causing toxicity.

In this case report, a 25-year-old transgender woman on testosterone-blocking therapy developed generalised hypertrichosis after starting ciclosporin for severe plaque psoriasis, illustrating that ciclosporin can induce this side effect even under androgen suppression.

In this case study, a 68-year-old woman with hyperandrogenism and presumed ovarian origin responded well to GnRH agonist therapy, normalizing testosterone levels and stabilizing blood pressure, suggesting its effectiveness as a non-surgical treatment option.

This study observed that serotonin signaling promoted hair shaft elongation and upregulated hair growth-related genes in dermal papilla cells, suggesting its potential role in advancing alopecia therapy.

In this prospective, placebo-controlled study, the researchers observed a significant reduction in hair shedding in women after applying the combined topical treatment DA-OTC-002, containing synephrine and TAAR agonists, compared to placebo, showing a 62.5% average reduction with no reported adverse events.

This study presents two adolescent cases of ovarian hyperthecosis, a rare cause of severe hyperandrogenism, highlighting management strategies involving gonadotropin suppression and hormone replacement after excluding androgen-producing adrenal and ovarian tumors.

This study found that engineered high-affinity soluble CD200R agonists, including ARQ-234, showed superior efficacy in reducing immune responses in various preclinical models of inflammatory conditions, suggesting potential as a therapeutic for atopic dermatitis and other related diseases.

This study reviewed existing literature to demonstrate that thyroid disorders have a significant and underestimated impact on hair loss, highlighting gaps in current knowledge and the need for further research to better diagnose and manage hair disorders linked to thyroid dysfunction.