Hirsutism And Hypertrichosis In Adults: Investigations And Treatment

    May 2002 in “ PubMed ”
    A. Bennet
    TLDR The document concludes that treatment for excessive hair growth depends on the cause, with options including hair removal methods and medications like anti-androgens or insulin-sensitizing drugs.
    The document from 2002 discusses the differences between hypertrichosis and hirsutism in adults, their causes, and treatments. Hypertrichosis, characterized by increased hair growth in non-androgen-dependent areas, does not require hormone level monitoring, unlike hirsutism, which involves increased hair growth in androgen-dependent areas. Hypertrichosis in adults can be caused by medications (minoxidil, ciclosporine, diazoxide, or glucocorticosteroids), metabolic issues (porphyria), nutritional problems (anorexia), or paraneoplastic syndromes (hypertrichosis lanuoginosa). Hirsutism can be caused by virilizing tumors, Cushing's syndrome, hyperprolactinemia, acromegalia, or late manifestation homozygous forms of a 21-hydroxylase (21OHD) block. Treatments for hirsutism can be local (discoloration, depilation, diathermo-coagulation, laser) or systemic, with the most effective treatments being anti-androgenic: cyproterone acetate, progesterone-like and anti-gonadotropic agents, spironolactone, and flutamide. Finasteride appears less effective. Other treatments include GnRH-agonists, dietetics, and metformine in cases of insulin-resistance.
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