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Glossary Insulin Resistance

condition where cells don't respond well to insulin

Insulin Resistance (IR) is a condition where the body's cells become less responsive to the hormone insulin, which is crucial for regulating blood sugar levels. As a result, the pancreas produces more insulin to compensate, leading to higher insulin levels in the blood and potentially progressing to type 2 diabetes. This condition is often associated with obesity, physical inactivity, and genetic factors.

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Research

5 / 1000+ results

Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Its Relation to Insulin Resistance

research Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Extent of Its Relation to Insulin Resistance

270 citations , April 2007 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that PCOS patients had higher amounts of central abdominal fat compared to weight-matched controls, which was associated with increased insulin resistance.

research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

222 citations , January 2014 in “International journal of reproductive medicine”

This paper reviews the complex pathophysiology of polycystic ovary syndrome, exploring how hormonal and metabolic disturbances contribute to its symptoms and related health risks, but it presents no new findings.

research Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity

195 citations , November 2019 in “Clinica Chimica Acta”

This review discusses the interplay of hyperandrogenism, insulin resistance, obesity, and their role in polycystic ovary syndrome, but presents no new clinical results.

research The influence of androgens on insulin resistance

135 citations , March 1984 in “Fertility and sterility”

In this study, insulin resistance in polycystic ovary syndrome was highly correlated with unbound testosterone and sex hormone-binding globulin, rather than luteinizing hormone or peripheral androgen metabolism.

research Early androgenetic alopecia as a marker of insulin resistance

115 citations , September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

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Community Join

5 / 198 results

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Does high sugar/insulin resistance or generally bad diet prevent fin/dut from working?

10 upvotes 9 months ago

A poor diet high in sugar and insulin resistance may reduce the effectiveness of finasteride in treating hair loss. Improving diet could potentially enhance treatment results.

community Anyone with high glucose, insulin resistance, pre-diabetes or diabetes notice any regrowth after starting treatment?

5 upvotes 1 year ago

A 21-year-old male with advanced hair loss (NW7) started using finasteride and minoxidil 10 months ago but hasn't seen much progress. He is pre-diabetic with stage 1 hypertension and is seeking insights on whether treating these conditions could improve hair regrowth.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 2 years ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

community Positive Hair Result in Patient using Tirzepatide

4 upvotes 1 year ago

A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.

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Learn

2 / 801 results

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Can metformin improve scalp health in people with insulin resistance or PCOS? There is no controlled trial showing that metformin improves scalp hair. The PCOS studies most often cited measured unwanted body hair, not scalp density, and a published case report describes hair loss during metformin treatment; any use for hair would be off-label and a decision for a prescribing doctor.

learn Inulin

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