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The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
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research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss
5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study
Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.
research Hypertrichosis in Females Applying Minoxidil Topical Solution and in Normal Controls
Minoxidil use increases facial hair growth in females, more in older users.
research Efficacy and Tolerability of Two Scalp Cooling Systems for the Prevention of Alopecia Associated with Docetaxel Treatment
Scalp cooling significantly reduces hair loss in chemotherapy patients.
research A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia
Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
research The Efficacy and Safety of JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis of Prospective Studies
Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.
research Topical Valproic Acid Increases Hair Count in Male Patients with Androgenetic Alopecia: A Randomized, Comparative, Clinical Feasibility Study Using Phototrichogram Analysis
Valproic acid increases hair count in men with hair loss.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research Tofacitinib for the Treatment of Severe Alopecia Areata in Adults and Adolescents
Tofacitinib shows promise for treating severe hair loss in adults and teens, with many experiencing regrowth, but hair loss returns when treatment stops.
research The Ins and Outs of Laser Hair Removal: A Mini Review
Laser hair removal is popular for long-term hair reduction but carries risks, requiring well-trained operators and better regulations, especially in South Africa.
research Maintenance, Withdrawal, and Re-Treatment with Ritlecitinib and Brepocitinib in Patients with Alopecia Areata in a Single-Blind Extension of a Phase 2a Randomized Clinical Trial
Continuous treatment with ritlecitinib and brepocitinib is needed to maintain hair regrowth in alopecia areata.
research Minoxidil for Patchy Alopecia Areata: Systematic Review and Meta-Analysis
Minoxidil effectively and safely treats patchy hair loss, but more research needed.
research Utility of Azathioprine, Methotrexate, and Cyclosporine as Steroid-Sparing Agents in Chronic Alopecia Areata: A Retrospective Study of Continuation Rates in 138 Patients
Azathioprine is the most continued treatment for chronic alopecia areata over a year, often with added low-dose prednisolone.
research Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial
Topical finasteride is an effective and safer treatment for male hair loss.
research Combined Effect of Microneedling and Platelet-Rich Plasma for the Treatment of Acne Scars: A Meta-Analysis
Using microneedling with platelet-rich plasma is more effective and just as safe as microneedling alone for treating acne scars.
research Efficacy of Superficial Cryotherapy on the Eyebrows of Patients With Alopecia Universalis Also Treated With Contact Immunotherapy on the Scalp: A Prospective, Split-Face Comparative Study
Superficial cryotherapy significantly improves eyebrow hair growth in alopecia universalis patients.
research Evaluation of Bioequivalence of Five 0.1 mg Dutasteride Capsules Compared to One 0.5 mg Dutasteride Capsule: A Randomized Study in Healthy Male Volunteers
Taking five small dutasteride capsules is the same as taking one larger capsule.
research Real-World Experience and Long-Term Evaluation of Tofacitinib in Refractory Alopecia Areata: A Prospective, Open-Label, Single-Center Study in Asian Arab Population
Tofacitinib is a promising treatment for severe alopecia areata, with many patients experiencing complete or partial hair regrowth.
research A Study to Assess the Efficacy of Fractional Carbon Dioxide Laser with Topical Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia
Using a carbon dioxide laser and platelet-rich plasma together can effectively restore hair and patients are generally satisfied with the results.
research Comment on 'Low Dose Oral Minoxidil for Treating Alopecia: A 3-Year North American Retrospective Case Series': Adding Further Evidence About Side Effects
Low-dose oral minoxidil for hair loss seems to have rare side effects, but more research is needed to confirm its safety.
research Drug Survival and Long-Term Outcome of Tofacitinib in Patients with Alopecia Areata: A Retrospective Study
Tofacitinib is effective and safe for treating alopecia areata with a good drug survival rate.
research Microneedling and Its Use in Hair Loss Disorders: A Systematic Review
Microneedling helps with hair loss, especially with 5% minoxidil, but more high-quality research is needed.
research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
research Neonatal Derived Mesenchymal Stem Cell Mesotherapy in Androgenetic Alopecia: A Retrospective Observational Study and Review of Literature
Neonatal mesenchymal stem cell therapy shows promise for treating hair loss but needs more research.
research Implementing Patient Safety and Quality Improvement in Dermatology: Part 1 - Patient Safety Science
The document concludes that improving patient safety and quality is increasingly important in dermatology.
research Treatments for Alopecia Areata: A Network Meta-Analysis
The analysis aims to identify the most effective and safest treatments for alopecia areata.
research Factors Predicting Response to Oral Methylprednisolone Tapering Treatment in Alopecia Areata: A Retrospective Study
Younger patients and those with more hair loss are less likely to benefit from oral steroid treatment for hair loss, and low vitamin D may predict relapse.
research Efficacy and Safety of Dupilumab in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis
Dupilumab is effective and safe for treating moderate-to-severe atopic dermatitis in adolescents.
research Cognitive Dysfunction Following Finasteride Use: A Disproportionality Analysis of the Global Pharmacovigilance Database
Finasteride use is linked to increased reports of cognitive problems, especially in younger people with hair loss.