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A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.

A woman's male-like physical changes were caused by two rare ovarian conditions.

Female hair loss patients more likely to have dry eye and gland issues.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Certain drugs that block specific enzymes can help treat prostate diseases.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.