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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Continuous research and innovative strategies are essential for sustainable development.

The conference emphasized innovative solutions for global challenges, including disaster architecture, education, health, and economic impacts.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Continued research and awareness are needed to improve treatments for androgen-dependent diseases.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.

Ganoderma lucidum extract may help treat stress-related hair loss.

Licorice has many health benefits but should be used carefully due to possible side effects.

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.