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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

DHT, a testosterone byproduct, causes male pattern baldness.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.

Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.

Oestrogens are key for bone growth during puberty in both boys and girls.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.

Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

The woman's high testosterone levels indicated PCOS, leading to treatment that improved her symptoms.

Finasteride significantly reduces hair growth in women with idiopathic hirsutism.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Hair loss is caused by genetics and hormones, diagnosed through examination and biopsy, and treated with medications or surgery.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.