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This review discusses how women with PCOS have an increased risk of insulin resistance and cardiometabolic features regardless of body fat, and calls for targeted prevention and management strategies.

This paper discusses potential links between fat distribution, adipocyte dysfunction, and inflammatory markers in PCOS patients, without presenting new clinical data.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

This study found that women with polycystic ovary syndrome have higher global adiposity and increased visceral fat, particularly in the ip and mesenteric depots, compared to women without androgen excess.

This letter to the editor reports an observation of alopecia occurring after treatment with deoxycholic acid for reducing submental fat, but it presents no new clinical data or broader conclusions.

This study observed that, among women of reproductive age with prediabetes, those treated with a combination of metformin and liraglutide experienced greater weight loss, a more significant decrease in visceral adiposity index, and higher rates of HbA1C normalization compared to those receiving metformin and inositol.

This review highlights the impact of obesity on skin health, detailing how it alters skin barrier function, exacerbates conditions like Psoriasis, and is linked to various skin complications without reporting new clinical results.

The authors concluded that increased expression of the HSD11B1 gene in adipose tissue correlates with obesity markers and predicts insulin resistance, but this association is independent of polycystic ovary syndrome when adiposity is controlled for.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

This study found that while intensive lifestyle interventions were associated with favorable changes in SHBG levels due to reduced adiposity, these changes did not consistently predict diabetes risk reduction.

This study found that both genetic and epigenetic factors significantly influence age-related facial skin aging, with lifestyle and environmental factors also playing a substantial role.

In this study, researchers identified two person-centered sexual function profiles among women, linked to physical and psychological factors, with PCOS showing greater, though not significant, presence in the dysfunction profile. The dysfunction was associated with higher adiposity and body-image distress.

This article discusses the complex aetiology, diagnostic criteria, and challenges in diagnosing polycystic ovary syndrome, but does not report new clinical findings.

This study found that women with polycystic ovary syndrome phenotypes A and B had the highest prevalence of metabolic syndrome, and that the visceral adiposity index may help predict metabolic risk.

This study found that deoxycholic acid effectively reduces excess fat under the chin, showing significant volume reduction and increased patient satisfaction in both aesthetic improvements and recovery experiences among the 13 participants.

This position statement reviews the role of exercise professionals in managing PCOS and provides recommendations for physical activity, but it reports no new clinical findings.

In this study, younger women with PCOS showed a 27% prevalence of abnormal glucose tolerance, with higher rates among those who are obese, have central adiposity, acanthosis nigricans, or a family history of diabetes.

This study identified genetic differences between Australian White Sheep and Hu Sheep that may explain their distinct pelage types, with a focus on subcutaneous adiposity and immunoregulation. The findings suggest potential targets for breeding climate-resilient sheep, enhancing our understanding of heat tolerance in these breeds.

This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.

This study found that a low dose of finasteride over 12 weeks did not alter the lipid profile or adiposity index in atheroprone Ldlr−/− mice.

In this large British study, prostate cancer risk was linked to ethnicity, family history, prostate enlargement, and PSA testing, while excess adiposity, smoking, diabetes, and certain lifestyle factors were associated with a reduced risk.

This study found that omega-6 and saturated fatty acid-enriched diets promote weight gain and certain skin changes regardless of gut microbiota, while omega-3 diets limit adiposity and affect skin in a microbiota-dependent way in mice, highlighting a diet–microbiota–lipid relationship in skin health.

This study found that while men's facial appearance, specifically attractiveness and masculinity, correlated with cardiometabolic indicators like insulin resistance and triglycerides, these links disappeared after adjusting for factors such as age, adiposity, and testosterone levels, suggesting that facial cues do not reliably indicate metabolic health.

This case report highlights a new manifestation of lipodystrophy in HIV patients: excess fat deposition in the anterior neck, which may have implications for treatment strategies.

This review explores the similarities between polycystic ovary syndrome and hemochromatosis in terms of iron overload and suggests that addressing gut dysbiosis might help manage iron levels in these conditions.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

This study found that women with polycystic ovary syndrome have a higher prevalence of non-alcoholic fatty liver disease and increased androgen bioavailability may be involved alongside metabolic factors.

This meta-analysis found a consistent positive association between glucocorticoids in hair and obesity measures, with the relationship between hair cortisone and waist circumference being particularly clinically relevant.

This review highlights the connection between sex hormones and metabolic dysfunction, emphasizing how conditions like male hypogonadism and female hyperandrogenism can increase the risk and severity of hepatic steatosis, which often progresses alongside metabolic syndrome and elevates mortality risks.