2 citations
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October 2022 in “Frontiers in genetics” This case report describes a 46-year-old Italian woman with congenital adrenal hyperplasia who experienced significant improvements in physical and psychological health after receiving a delayed diagnosis and subsequent treatment.
November 2025 in “Medicina” This study found that patients with alopecia areata had a lower heart rate compared to healthy controls and showed disease-severity-related changes in body composition, though the clinical importance of these findings is still unclear.
September 2020 in “Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi” This review investigates the relationship between certain gene polymorphisms associated with obesity (FTO and MC4R) and Polycystic Ovarian Syndrome, reporting no new results but suggesting a potential genetic link.
March 2013 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This review discusses the role of various hormones in diffuse hair loss and emphasizes the need for further research to clarify their complex interactions and potential therapeutic implications, but reports no new clinical results.
March 2015 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This article discusses testosterone production in the human body and its effects on muscle mass, bone density, metabolism, and skin, but reports no new findings.
23 citations
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January 2017 in “Current Rheumatology Reports” This study found that adipocytes in the interfacial white adipose tissue adjacent to fibrotic lesions in systemic sclerosis show unique phenotypes and contribute to the condition's pathogenesis.
198 citations
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July 2011 in “Cochrane library” This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.
28 citations
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November 2013 in “The FASEB journal” In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.
4 citations
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March 2020 in “BMC Research Notes” In this study of Irish adults with morbid obesity, skin tags were associated with higher blood pressure, HbA1c levels, and a greater prevalence of diabetes and hypertension, indicating increased cardiovascular risk.
August 2025 in “Scire Salutis” In this study, researchers reviewed recent literature to investigate the influence of childhood and adolescent obesity on acne development, noting that excess body fat may contribute to acne through hormonal changes, inflammation, and metabolic dysfunction.
February 2020 in “Diabetologie Und Stoffwechsel” This article reviews treatment strategies for polycystic ovary syndrome, specifically recommending letrozole for infertility, while also discussing lifestyle changes and other potential therapies, and reports no new research findings.
December 2023 in “Journal of Volgograd State Medical University” This study reviewed current research on white, brown, and beige adipose tissue, highlighting their roles in metabolism, thermogenesis, tissue repair, and stem cell activity, and identified the study of adiponectins as important for advancing knowledge of metabolic syndrome and tissue regeneration mechanisms.
April 2026 in “Diagnostics” This study found that skin changes in morbidly obese individuals are associated with underlying metabolic disturbances but are not currently valuable as independent tools for assessing metabolic risk or treatment response.
March 2023 in “Здобутки клінічної і експериментальної медицини” This study found that in adolescents with excess weight and obesity, vitamin D levels are inversely correlated with leptin and positively correlated with adiponectin, influencing metabolic exchange criteria.
September 2019 in “Journal of evolution of medical and dental sciences” In this study of patients with obesity, the most common skin disorders observed were acanthosis nigricans, skin tags, and stretch marks, emphasizing the impact of obesity on dermatological health.
26 citations
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June 2014 in “Fertility and Sterility” In this study, normal weight adolescents with PCOS showed increased insulin resistance and significantly lower levels of high molecular weight adiponectin compared to controls, despite no other metabolic differences.
405 citations
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May 2007 in “Journal of The American Academy of Dermatology” This review discusses the profound impact of obesity on skin physiology and dermatologic conditions and reports no new experimental results, recommending awareness and treatment strategy development for obesity-associated dermatoses.
403 citations
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November 2005 in “Journal of Endocrinology” This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.
374 citations
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May 2016 in “The Lancet. Diabetes & endocrinology” This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.
356 citations
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September 2014 in “Journal of Clinical Research in Pediatric Endocrinology” This article discusses the rising prevalence and serious implications of childhood obesity and reports no new experimental findings; the authors emphasize the importance of prevention and early intervention through comprehensive management programs.
286 citations
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January 2009 in “Human Reproduction Update” This study reports that NIH PCOS is linked to more severe metabolic issues, including higher obesity and insulin resistance, compared to non-NIH PCOS phenotypes.
218 citations
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May 2014 in “Experimental Dermatology” This review explores the evolution and development of skin-associated adipose tissue and proposes new nomenclature for the cells and adipose tissue underlying the reticular dermis, without reporting clinical results.
114 citations
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January 2014 in “World Journal of Gastroenterology” This study highlights the potential increased frequency of advanced liver disease in obese PCOS patients with NAFLD and underscores the importance of lifestyle modifications as initial treatment.
110 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
50 citations
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August 2017 in “Diabetologia” This review discusses genetic factors that may influence the effectiveness of metformin in treating polycystic ovary syndrome and emphasizes the need for further research to establish clear benefits.
46 citations
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January 2008 in “Journal of cosmetic dermatology” Caffeine and siloxanetriol alginate caffeine in emulsion form can reduce fatty cell size and number, potentially treating cellulite effectively.
44 citations
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March 2008 in “European journal of endocrinology” This study found that women with PCOS had lower fasting serum ghrelin levels and a reduced ghrelin response to an oral glucose load compared to controls, with an inverse relationship to insulin resistance.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” This review explores the potential of selective 11β-HSD1 inhibitors to improve insulin sensitivity in type 2 diabetes, emphasizing the need for more clinical research and reports no new clinical results.
36 citations
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May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
32 citations
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June 2015 in “PLOS ONE” This study demonstrated that topical oleuropein induced hair growth in mice by activating the Wnt10b/β-catenin signaling pathway and increasing expression of several growth-related genes in skin tissue.