31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.
29 citations
,
January 2009 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have significantly higher plasma levels of thrombin-activatable fibrinolysis inhibitor and other hemostatic markers compared to age- and BMI-matched healthy controls.
28 citations
,
November 2007 in “Medical Clinics of North America” This review discusses the impact, pathophysiology, and health risks of obesity and the metabolic syndrome in polycystic ovarian syndrome, emphasizing the potential life-saving benefits of recognition and treatment, but it reports no new results.
19 citations
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January 2005 in “Paediatrics and Child Health” This review discusses the features and diagnosis of metabolic syndrome in obese children and reports no new findings, highlighting the need for a uniform pediatric definition and early intervention.
17 citations
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February 2019 in “Journal of Clinical Medicine” This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.
16 citations
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October 2020 in “Lipids in Health and Disease” This review explores the current understanding of leptin's role in psoriasis and other skin diseases but reports no new clinical findings, emphasizing that the exact mechanisms of its impact are still being investigated.
15 citations
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January 2002 in “Gynecological endocrinology” This review discusses the extragenital effects of ovarian steroids, particularly focusing on aesthetic endocrinology, which suggests estrogens may slow skin aging post-menopause, though hair loss treatment efficacy is mainly confirmed for minoxidil.
14 citations
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January 2018 in “Advances in Clinical Chemistry” This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.
12 citations
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April 2014 in “Facial Plastic Surgery Clinics of North America” This review evaluates neck rejuvenation techniques, including cervical rhytidectomy, and discusses potential surgical complications, without presenting new clinical findings.
11 citations
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October 2003 in “Postgraduate Medical Journal” This study described four cases of delayed diagnosis of Cushing’s syndrome, highlighting that increased clinical awareness and screening could reduce its associated morbidity and mortality.
9 citations
,
August 2024 in “Australian Prescriber” This review highlights that pharmacotherapy for polycystic ovary syndrome should address individual patient concerns, with metformin beneficial for reducing weight and metabolic risk, and lifestyle modifications also important.
9 citations
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January 2015 in “Springer eBooks” This article reviews the diagnostic criteria and management strategies for polycystic ovary syndrome but reports no new clinical findings; it highlights associated health risks and recommended treatments.
9 citations
,
November 2012 in “Archives of Dermatological Research” MC4R gene variants not linked to female hair loss.
3 citations
,
March 2007 in “Canadian Medical Association Journal” This abstract provides background information on polycystic ovary syndrome and reports no new research findings.
2 citations
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June 2009 in “The Nurse practitioner” This article highlights that many women with PCOS are unaware of their condition and its increased risks for type 2 diabetes and cardiovascular disease, and it offers no new clinical findings.
May 2026 in “Research Square” In this study of women aged 18-45 from an endocrine referral group, researchers found that while clinical hirsutism severity is independently associated with biochemical hyperandrogenism, the relationship is modest and suggests different biological aspects are at play.
May 2026 in “AlQalam Journal of Medical and Applied Sciences” In this study, researchers found that relying solely on ferritin to assess iron status in young females with higher BMI may lead to inaccurate diagnoses of iron deficiency due to inflammation-related ferritin elevation.
October 2025 in “Scientific Reports” In this study of 131 healthy men aged 30 to 45, no relationship was found between androgen receptor gene polymorphisms related to androgen sensitivity and biological age markers, suggesting that other factors may influence the aging process independently of these genetic variations.
This study synthesizes current evidence showing that menopause involves a predictable endocrine transition, while male ageing features a more variable testosterone decline, necessitating a nuanced clinical approach to diagnosis and treatment.
August 2024 in “Qucosa (Saxon State and University Library Dresden)” In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.
October 2023 in “ANNALS OF PAKISTAN MEDICAL & ALLIED PROFESSIONALS” This study found that in women with PCOS, insulin resistance is closely associated with hyperandrogenism, indicating it may independently predict increased androgen levels.
November 2022 in “Journal of the Endocrine Society” This case report describes a patient with ectopic Cushing's syndrome who experienced fatal complications from COVID-19, highlighting the challenges in managing such patients due to immune response alterations from endogenous hypercortisolemia.
December 2020 in “Innovation in aging” This study suggests that inhibiting PKC, similar to rapamycin treatment, can extend lifespan and reduce neurological symptoms and inflammation in mice with mitochondrial dysfunction, potentially involving the mTORC2 pathway.
January 2020 in “Research Square (Research Square)” In this study, Irish adults with severe obesity who had cervical or axillary skin tags showed higher systolic blood pressure, higher HbA1c levels, and more diabetes and hypertension, suggesting an increased vascular risk.
July 2019 in “International Journal of Advance Research in Community Health Nursing” This study observed that, among women in Padgampora Village, J&K, aged 15-45, 42.5% had PCOS between ages 15 and 25, with clinical signs like irregular cycles, obesity, acne, and more, highlighting the need for increased awareness and early intervention.
July 2017 in “Cardiologia Croatica” This review discusses the components and risks of metabolic syndrome and emphasizes lifestyle changes as a primary treatment approach; it reports no new clinical results.
February 2016 in “Evidence Based Women Health Journal (Online)” This study observed that women with polycystic ovarian syndrome had higher serum SRAGE levels compared to controls, but the difference was not statistically significant.
This abstract contains subscription and access information for Wolters Kluwer Health journals but reports no research findings.
September 2008 in “Fertility and Sterility” This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.
53 citations
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June 2012 in “Annales d'Endocrinologie” This review discusses the range and causes of adipose tissue diseases, emphasizing genetic and acquired forms of lipodystrophy, but it reports no new clinical results.