9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
6 citations,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
29 citations,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
106 citations,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
30 citations,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
20 citations,
May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
1 citations,
November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
3 citations,
March 2023 in “Life” Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
182 citations,
June 2017 in “Biomaterials” Special fiber materials boost the healing properties of certain stem cells.
2 citations,
May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
25 citations,
August 2010 in “Acta Biomaterialia” Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
47 citations,
March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
45 citations,
March 2020 in “ACS Applied Materials & Interfaces” The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.
9 citations,
March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
10 citations,
December 2011 in “Cell Transplantation” Researchers successfully grew human hair follicle cells that could potentially lead to new hair loss treatments.
9 citations,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
130 citations,
November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
87 citations,
July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
21 citations,
April 2011 in “Physiological Research” Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
3 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
115 citations,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
8 citations,
June 2023 in “Journal of clinical medicine” Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.