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    Glossary Adenylate Cyclase

    enzyme converting ATP to cAMP, crucial for cell signaling

    Adenylate Cyclase (AC) is an enzyme found in cell membranes that converts ATP (adenosine triphosphate) into cyclic AMP (cAMP). This conversion is crucial because cAMP acts as a second messenger in various biological processes, including the regulation of metabolism, gene expression, and cell growth.

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    1. 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells 2002 · 18 citations
    2. Finasteride inhibits melanogenesis through regulation of the adenylate cyclase in melanocytes and melanoma cells Archives of Pharmacal Research · 2018 · 11 citations
    3. Testosterone regulates levels of cystic fibrosis transmembrane regulator, adenylate cyclase, and cAMP in the seminal vesicles of orchidectomized rats Theriogenology · 2015 · 11 citations
    4. Lithium therapy associated with hidradenitis suppurativa: Case report and a review of the dermatologic side effects of lithium Journal of The American Academy of Dermatology · 1995 · 64 citations
    5. Several Selective Protein Kinase C Inhibitors Including Procyanidins Promote Hair Growth Skin pharmacology and physiology · 2000 · 32 citations
    6. Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland International journal of endocrinology · 2022 · 1 citations
    7. Enzymes British Journal of Pharmacology · 2008
    8. Dopamine is a novel, direct inducer of catagen in human scalp hair follicles<i>in vitro</i> British Journal of Dermatology · 2012 · 19 citations
    9. Adverse Dermatologic Effects of Cardiovascular Drug Therapy: Part III Cardiology in Review · 2002 · 15 citations
    10. Urinary steroids in men with male-pattern alopecia Journal of Biochemical and Biophysical Methods · 2002 · 13 citations
    11. In This Issue Proceedings of the National Academy of Sciences of the United States of America · 2007
    12. Potential role and therapeutic interests of myo-inositol in metabolic diseases Biochimie · 2013 · 369 citations
    13. Melatonin membrane receptors in peripheral tissues: Distribution and functions Molecular and Cellular Endocrinology · 2012 · 506 citations
    14. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006 · 375 citations
    15. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun ˜The œFASEB journal · 2005 · 349 citations
    16. Melatonin in the skin: synthesis, metabolism and functions Trends in Endocrinology and Metabolism · 2008 · 252 citations
    17. Vitamin D metabolism and function in the skin Molecular and cellular endocrinology · 2011 · 185 citations
    18. Erectile Dysfunction in Young Men—A Review of the Prevalence and Risk Factors Sexual Medicine Reviews · 2017 · 176 citations
    19. Caffeine’s Mechanisms of Action and Its Cosmetic Use Skin Pharmacology and Physiology · 2012 · 153 citations
    20. Estrogens and aging skin Dermato-endocrinology · 2013 · 150 citations
    21. Neural Mechanisms of Hair Growth Control Journal of Investigative Dermatology Symposium Proceedings · 1997 · 101 citations
    22. Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone Journal of Investigative Dermatology · 2008 · 98 citations
    23. Olfactory receptor OR2AT4 regulates human hair growth Nature Communications · 2018 · 82 citations
    24. PAK4 signaling in health and disease: defining the PAK4–CREB axis Experimental & Molecular Medicine · 2019 · 81 citations
    25. Adverse effects of common medications on male fertility Nature Reviews Urology · 2015 · 77 citations
    26. Oestrogen functions in skin and skin appendages Expert Opinion on Therapeutic Targets · 2005 · 68 citations
    27. Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways Journal of Molecular Medicine · 2007 · 66 citations
    28. Small molecules and small molecule drugs in regenerative medicine Drug Discovery Today · 2013 · 51 citations
    29. Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse 2016 · 36 citations
    30. Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease Thrombosis Research · 2015 · 35 citations