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GlossaryCyclic Adenosine Monophosphate (cyclic AMP)

acts as a second messenger in cellular signal transduction

Cyclic Adenosine Monophosphate (cAMP) is a crucial cellular messenger that helps transmit signals from the cell surface to its interior, influencing various biological processes such as metabolism, gene expression, and cell growth. In the context of hair biology, cAMP plays a role in regulating hair follicle activity and can impact conditions like alopecia by affecting hair growth cycles.

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research Effects of Dobutamine on Cyclic AMP Accumulation Induced by the Stimulation of Dopamine Receptors in Rabbit Retina In Vitro

3 citations , September 1980 in “Experientia”

Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.

research Interaction of Alpha-Melanocyte-Stimulating Hormone, Melatonin, Cyclic AMP and Cyclic GMP in the Control of Melanogenesis in Hair Follicle Melanocytes In Vitro

53 citations , July 1981 in “Journal of Endocrinology”

α-MSH and cyclic AMP boost melanin production, while cyclic GMP and melatonin reduce it.

research Micro-Determination of Cyclic AMP Levels in Human Epidermis, Dermis, and Hair Follicles

19 citations , March 1975 in “British Journal of Dermatology”

A new method accurately measures cyclic AMP levels in small skin and hair samples.

research Interleukin-1β-Induced Inhibition of Hair Growth In Vitro Is Mediated by Cyclic AMP

33 citations , January 1997 in “Journal of Investigative Dermatology”

research Cyclic Nucleotides and the Mediation of Melatonin-Induced Inhibition of Melanogenesis in Mammals

1 citations , January 1981 in “Elsevier eBooks”

Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.

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community 6.5 Month Progression 33/Female

in Female 44 upvotes 2 years ago

Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

community Fin and Oral Minoxidil completely changed my hair texture (8months progress)

in Progress Pictures 353 upvotes 1 year ago

Finasteride and oral minoxidil significantly improved hair texture and thickness over 8 months. The user also experienced increased hair growth on the beard and eyebrows.

community (M28) 3 months progress on minoxidil 5%

in Progress Pictures 76 upvotes 1 year ago

A 28-year-old male showed hair regrowth after 3 months using 5% liquid minoxidil twice daily and weekly dermarolling with a 1mm roller. Someone suggested adding finasteride to the treatment.

community Meta analysis: Topical or mesotherapy dutasteride is more effective than topical finasteride in the treatment of AGA in men

in Research/Science 18 upvotes 3 years ago

Topical Dutasteride is more effective than topical Finasteride for treating AGA in men, with fewer side effects. Mesotherapy with Dutasteride, administered every 3 months, shows promising results for hair regrowth and maintenance without daily routines or significant side effects.

community 6 Month results video (47 y/o, 46 when I started). Various products, discontinued due to scalp irritation and eventually landed on Fin/Min spray starting at week 6. Dermarolled 0.50mm once per week.

in Progress Pictures 364 upvotes 1 year ago

A 47-year-old user shared their 6-month hair loss treatment results using a Fin/Min spray and weekly dermarolling. They experienced scalp irritation with other products but found success with the Hims Fin/Min spray, noting improvements around the 5th month.