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research INTERACTION OF α-MELANOCYTE-STIMULATING HORMONE, MELATONIN, CYCLIC AMP AND CYCLIC GMP IN THE CONTROL OF MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO

53 citations , July 1981 in “Journal of Endocrinology”

In this study, α-MSH and cyclic AMP were found to stimulate melanogenesis in hair follicle cultures, while cyclic GMP and melatonin inhibited melanin production but not tyrosinase activity.

research Micro-determination of cyclic AMP levels in human epidermis, dermis and hair follicles

19 citations , March 1975 in “British Journal of Dermatology”

This study presents a method for extracting and measuring cyclic AMP in small amounts of skin tissue, finding varying levels in the dermis, epidermis, and hair follicles.

research Effects of dobutamine on cyclic AMP accumulation induced by the stimulation of dopamine receptors in rabbit retina in vitro

3 citations , September 1980 in “Experientia”

In this study, the pharmacological action of dobutamine on rabbit retinae was found to be distinct from that of other dopamine analogs like apomorphine and N-methyl-dopamine.

research Interleukin-1β-Induced Inhibition of Hair Growth In Vitro Is Mediated by Cyclic AMP

33 citations , January 1997 in “Journal of Investigative Dermatology”

Interleukin-1β stops hair growth by increasing cyclic AMP levels.

research Cyclic Nucleotides and the Mediation of Melatonin-induced Inhibition of Melanogenesis in Mammals

1 citations , January 1981 in “Elsevier eBooks”

Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.

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community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

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