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This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.

This review of the JEADV editorial report highlights the journal's significant growth in submissions, quality, and impact over the course of the pandemic, but offers no new research findings.

This publication is a letter discussing the association between an androgen receptor genetic variant and COVID-19 disease severity in hospitalized male patients, but it reports no new research results.

In this case report, researchers described a treatment for post-aplasia cutis congenita alopecia using follicular unit transplantation, platelet-rich plasma, and fat grafting, which significantly improved hair follicles, skin quality, and sensitivity in the affected scalp area.

This review highlights that deucravacitinib, a selective TYK2 inhibitor, shows promise as an effective treatment for psoriasis and other inflammatory skin diseases, though real-world evidence beyond psoriasis is still emerging.

In this study, acellular dermal matrix hydrogels significantly improved healing in a rat model of radiation-induced skin injury by promoting angiogenesis and modulating inflammation, suggesting potential as a novel treatment for this common radiotherapy complication.

This study observed that treating acne scars with fractional ablative laser concurrently with isotretinoin improved outcomes more effectively compared to applying the laser 6 months after isotretinoin treatment ended, as measured by the Quantitative Global Acne Scarring Grading System.

This study found that c-Jun is essential for vitamin D receptor expression, and the vitamin D receptor inhibits c-Jun-dependent cell death through non-classical mechanisms independent of vitamin D3.

In this report, a rare case of scalp arteriovenous fistula following hair transplantation was successfully treated using direct puncture embolization with n-butyl cyanoacrylate glue, demonstrating effective management of this condition.

This case report describes a 39-year-old female with cutis verticis gyrata and cicatricial alopecia, emphasizing the need for further understanding of the potential genetic associations and underlying mechanisms.

AKR1B10 enzyme may cause keloid scars and could be a treatment target.

This study found that in a mouse model with hereditary 1,25-dihydroxyvitamin D resistant rickets, a mutant vitamin D receptor lacking hormone-binding ability could restore normal hair cycling and affect parathyroid hormone regulation.

This case report illustrates the diagnostic challenges and importance of early detection in primary vitreoretinal lymphoma, highlighting a successful treatment outcome with systemic chemotherapy in preventing CNS progression.

In this case report, researchers identified Vitamin A toxicity as the cause of refractory hypercalcemia in a nonverbal patient, emphasizing the difficulty of diagnosing this rare condition due to its nonspecific symptoms.

This study used cryo-electron microscopy to reveal the structural mechanisms by which TRPV6 and TRPV3 ion channels open, close, and are regulated, providing insights for potential future research.

This study identified a specific SNP in the CACNB4 gene associated with a higher risk of chemotherapy-induced alopecia in breast cancer patients, which may help develop interventions to improve their quality of life.

In their mouse study, Oda et al. found that removing the MED1 gene in the skin led to hair loss and changes in epidermal cell differentiation, indicating MED1's significant role in these processes.

In this study, researchers identified CENPV as a new CYLD interacting partner that localizes to primary cilia and regulates acetylated tubulin levels, offering insights into the pathogenesis of skin appendage tumors.

This study found that mutations in the PADI3 gene, which is important for hair shaft formation, may contribute to central centrifugal cicatricial alopecia among patients.

In this study, researchers found that crude extracts from Avicennia marina and its component avicequinone C inhibit mechanisms contributing to androgenic alopecia in vitro, including 5α-reductase activity and DHT-AR interactions, potentially promoting hair growth and delaying the catagen phase in human dermal papilla cells.

In this study, researchers identified similar presence of various nicotinic and muscarinic AChRs in lesional and normal epidermis, suggesting that tobacco-delivered nicotine may exacerbate acne inversa by interacting with endogenously produced acetylcholine.

This study identified novel compound heterozygous mutations in the hairless gene among a non-consanguineous Chinese family with congenital atrichia, illustrating phenotypic variations due to founder or modifier genes.

This study, conducted at Montefiore Medical Center, reports that central centrifugal cicatricial alopecia predominantly affects middle-aged Black or African American women, often presenting without symptoms, which may delay diagnosis and treatment. The study underscores the need for a specific ICD-10 code for better epidemiological studies.

In this retrospective cohort study, 53.8% of adult rosacea patients who started CGRP monoclonal antibodies for migraines experienced improvement in papules/pustules and erythema/flushing, although moderate adverse events were noted, suggesting these antibodies may benefit rosacea symptoms.

In this study, researchers developed a mouse model of scarring alopecia and observed significant reductions in CD200R expression in affected skin, potentially linking this signaling pathway to immune attacks on hair follicles and suggesting new treatment targets for scarring hair loss.

This study found that ACOD1 deficiency in dermal papilla cells promotes mitochondrial dysfunction and contributes to cellular senescence in androgenetic alopecia, suggesting ACOD1 as a potential therapeutic target and 4-octyl itaconate as a promising treatment option for AGA.

In this case report, researchers observed that a 35-year-old male with alopecia universalis achieved full regrowth of scalp, eyebrow, and facial hair with oral upadacitinib treatment after previous therapies failed to provide lasting relief.

This study demonstrates that the CRISPR-Cas9 system can be used to successfully edit genes in large mammals, such as Cashmere goats, creating a valuable model for research on EDAR gene-related phenotypes.

This case study describes an extremely rare instance of androgen-secreting adrenocortical carcinoma in a patient with non-classical congenital adrenal hyperplasia.

This study found that SNPs in the MVK, ARPC1B, and CA2 genes may indicate a genetic predisposition for severe acne related to steroidogenesis.