A Vitamin to Consider: Refractory Hypercalcemia from Vitamin A Toxicity

    May 2024 in “ Endocrine practice
    Wafa Latif, Chinenye Usoh
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    TLDR Vitamin A toxicity can cause serious health issues like hypercalcemia and is often overlooked.
    The document discusses a rare case of Vitamin A toxicity leading to refractory hypercalcemia in a 19-year-old male with multiple health conditions, including cerebral palsy and spastic paraplegia. Despite extensive prior evaluations, the cause of his persistent hypercalcemia remained unidentified until elevated Vitamin A levels were discovered. This case underscores the importance of considering Vitamin A toxicity in the differential diagnosis of hypercalcemia, particularly in patients with atypical presentations or limited communication abilities. The patient's condition improved after switching to a low Vitamin A formula and receiving intravenous treatments. The study advocates for a more inclusive diagnostic approach in hypercalcemic patients.
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