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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Skin fat helps with body temperature control and has other active roles in health.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.