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Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Certain proteins are essential for the growth of root hairs in barley.

Combining laser hair removal with topical eflornithine is recommended for better results in treating unwanted facial hair.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Urokinase, a type of protein, helps skin cells multiply faster, especially in newborn mice.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.