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This study found that lncRNA H19 may regulate CTGF expression in KGN cells by acting as a "sponge" for miR-19b, potentially influencing polycystic ovary syndrome development.

This study found that topical curcumin can initiate hair growth in mice by acting as a JAK inhibitor but could not fully reverse alopecia areata, likely due to insufficient penetration to deeper skin layers.

Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.

This study found that a nomogram prediction model based on clinical characteristics, bone metabolism, and ovarian function can effectively predict the treatment response to long-acting GnRHa in girls with idiopathic central precocious puberty.

This study formulated and characterized a dutasteride-loaded nanocrystalline suspension for long-acting parenteral delivery, finding that it provided sustained drug release in rats with a significant reduction in local inflammation over 28 days following intramuscular injection.

The study found that, unlike in actinic keratosis and squamous cell carcinoma, basal cell carcinoma tissues showed higher expression of nidogen1 and Col4 in both basement membranes and surrounding stroma compared to normal skin.

This study suggests that testosterone may reduce knee joint range of motion by acting on relaxin receptors in rats, while flutamide and finasteride counteracted this effect and increased receptor expression.

This study shows that BMP2 and BMP7 play complex, necessary roles in feather development by regulating dermal condensation formation, with BMP7 acting early as a chemoattractant and BMP2 halting cell migration.

This study found that Sonic Hedgehog secreted by hair follicle transit-amplifying cells is essential for dermal adipogenesis and hair follicle growth by acting on adipocyte precursors.

This review evaluates previous studies on androgen-progestin combinations for male contraception, concluding that long-acting injectable formulations appear promising due to their effectiveness and minimal short-term adverse effects.

This study reported that specific non-coding RNAs may regulate the hair follicle cycle in Angora rabbits by acting as competitive endogenous RNAs, enhancing understanding of ncRNA roles in hair growth.

This review discusses developments in testosterone therapy, including the shift towards transdermal therapies and long-acting injectables, but reports no new clinical findings; emerging therapies are in development.

This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.

This case report suggests that imiquimod cream 5% may cause telogen effluvium as a rare side effect after treating actinic keratosis on the scalp.

This report discusses the FDA's third denial of approval for Aveed, a long-acting testosterone injection by Endo Pharmaceuticals, citing continued safety concerns including severe side effects.

This study identified hypericin and berberine as compounds that can support hair growth by enhancing oxytocin receptor expression and acting as an oxytocin receptor agonist, respectively, potentially serving as practical alternatives to oxytocin for treating hair-loss diseases.

This study suggests that certain gut microbiota may influence androgenic alopecia, potentially acting as protective or risk factors, and indicates opportunities for developing microbiota-based treatments.

This study suggests that the transcription factor PDF2 in Arabidopsis may link lipid sensing with growth responses to phosphate starvation by acting as a sensor for lyso-PCs through its START domain.

This review article found that fire needle acupuncture has shown promise in treating alopecia areata by acting directly on skin lesions and regulating Qi and blood, aiming to offer diagnostic and treatment insights for managing the condition.

This study found that actomyosin contractility in suprabasal keratinocytes influences the proliferation and differentiation of epidermal stem/progenitor cells by acting as a niche element in the skin.

In male mice and rats, this study found that 17α-estradiol improves metabolic health by acting through estrogen receptor α, suggesting a potential target for treating chronic diseases in male mammals.

This study found that while both conventional care and teledermatology showed similar clinical response rates for treating actinic keratosis with imiquimod 5% cream, teledermatology was associated with higher treatment failure and local reaction rates.

This report discusses the FDA's rejection of Aveed, a long-acting testosterone injection, due to safety concerns despite divided advisory committee opinions, without presenting new clinical data.

In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.

In this study, the researchers reported that Notch/CSL signaling is crucial for hair follicle differentiation, with Wnt5a signaling and FoxN1 acting as mediators in mice.

This study found that estrogen receptor beta plays a significant role in murine hair growth control, potentially acting as a silencer of estrogen receptor alpha's catagen-promoting effects.

In this study, minoxidil sulfate was found to relax norepinephrine-induced contractions in rabbit mesenteric arteries, possibly by acting as a K+ channel agonist, but it did not relax K+-induced contractions.

This review discusses how targeting TGF-β with specific inhibitors, including components from Traditional Chinese Medicine, may help reduce liver fibrosis by acting through various signaling pathways.

This study found that bolandiol increased lean body mass and bone mineral density in castrate adult male rats, exhibiting tissue selectivity and acting through multiple receptor pathways with less potency compared to other androgens.

This research suggests that both proposed pathways into hair fibers for molecule penetration are valid and complementary, with all fiber structures acting as potential routes for delivering materials.