Causal Relationship Between Gut Microbiota And Androgenic Alopecia: A Mendelian Randomization Analysis

This study explores the causal relationship between gut microbiota and androgenic alopecia (AGA) using Mendelian randomization analysis. The research identifies several gut microbiota taxa that may act as protective factors against AGA, including Oxalobacteraceae, Paraprevotella, Eubacterium ventriosum group, Lachnospiraceae UCG008, and Clostridiales, while Coriobacteriaceae may increase the risk of AGA. The analysis shows no significant heterogeneity or horizontal pleiotropy, indicating robust results. The findings suggest potential pathways for AGA influenced by gut microbiota, opening avenues for microbiota-based therapeutic strategies. The study did not receive any funding and declares no competing interests.