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PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Microneedles are being used and tested for various medical and cosmetic treatments.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.

Cannabinoids may help treat various skin conditions.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Fullerenes show potential in skin care but need more safety research.