7 citations
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January 2013 in “Egyptian Journal of Dermatology and Venereology” This study found that male patients with androgenetic alopecia had significantly higher aldosterone levels and blood pressure compared to controls, suggesting a possible link between AGA and hypertension.
1 citations
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January 2020 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” This study found that Aminexil clinical 5 significantly reduced hair loss in men and women with mild alopecia and was well tolerated with high subject satisfaction.
July 2018 in “Journal of Evolution of medical and Dental Sciences” In this study, researchers observed that men with androgenetic alopecia had a higher prevalence of metabolic syndrome compared to those without alopecia, which may warrant early screening for metabolic syndrome to prevent coronary artery disease, despite the study's small sample size.
This study found that Clitocybin A from Clitocybe aurantiaca significantly increased the proliferation of immortalized rat dermal papilla cells, suggesting potential hair growth-promoting effects in a laboratory setting.
14 citations
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March 2016 in “Journal of Dermatology” This study found that Korean patients with androgenetic alopecia had higher rates of cardiovascular diseases and related risk factors than those without the condition, with variations by severity and type of hair loss.
October 2021 in “QJM: An International Journal of Medicine” This study found that N-acetyl-cysteine alone or combined with minoxidil improved hair parameters in men with early-onset androgenetic alopecia, with tolerable side effects.
March 2026 in “International Journal of Dermatology and Venereology” This study found that abrocitinib showed promising efficacy and safety in adolescents with moderate-to-severe alopecia areata, with significant hair regrowth observed over 10 months of treatment.
July 2023 in “Institutional Repositories DataBase (IRDB)” Malassezia species may contribute to hair loss in AGA patients.
4 citations
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January 2016 in “Annals of Dermatology” This study found that men with more advanced androgenetic alopecia had increased epicardial fat thickness, suggesting a potential link to coronary risk.
This review discusses the characteristics and management of adolescent androgenetic alopecia, noting a lack of FDA-approved treatments and reporting no new clinical results.
December 2025 in “The Journal of Nutritional Biochemistry” This study found that kaempferol may stimulate hair growth in androgenetic alopecia by enhancing dermal papilla cell function and reducing dihydrotestosterone-induced damage, showing comparable efficacy to finasteride in a mouse model.
January 2019 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that the treatment group experienced a higher average increase in hair counts than the placebo group, but the difference was not statistically significant.
19 citations
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April 2023 in “Antibiotics” This study found that azelaic acid entrapped in transethosomes exhibited enhanced antidermatophyte activity and improved treatment outcomes in guinea pig models of dermatophytosis compared to free azelaic acid.
July 2025 in “Journal of Education Health and Sport” This review found that androgenetic alopecia may be associated with increased risks of cardiovascular disease, metabolic disorders, and mental health impacts, suggesting its potential as a biomarker for systemic conditions.
September 2002 in “Oncology Times” This study presented at the ASCO Annual Meeting reported that the epidermal growth factor receptor antibody ABX-EGF showed preliminary efficacy in renal cell cancer patients, with tolerable side effects, while bortezomib demonstrated clinical benefit in a significant proportion of multiple myeloma patients.
January 2020 in “프로그램북(구 초록집)” This study reported that educating patients about androgenetic alopecia treatment options increased awareness of the ineffectiveness of hair cosmetics and their perceived cost.
This study found that androgenetic alopecia in Chinese college students is more prevalent in males and is significantly associated with rosacea, with clinic patients experiencing a higher disease burden.
4 citations
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May 2002 in “Therapeutische Umschau” AGA treated with finasteride, minoxidil, and hair transplantation.
April 2025 in “Annals of Medicine” This study assessed the combination of compound glycyrrhizin and conventional treatments for alopecia areata and found it effective for promoting hair regrowth while being safe with mild adverse effects, based on a systematic review and meta-analysis of randomized controlled trials.
October 2025 in “Asian Journal of Oral Health and Allied Sciences” In this case report, a 28-year-old male with androgenetic alopecia showed improved hair density and shaft thickness after four monthly sessions of autologous growth factor concentrate injections, with no adverse effects and high patient satisfaction, suggesting the treatment’s promise as a safe and effective option.
45 citations
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July 2025 in “Journal of Medicinal Chemistry” This article discusses the development and clinical progress of PROTAC technology, particularly focusing on the New Drug Application for vepdegestrant, an estrogen receptor-targeting PROTAC, marking significant advancements in targeted protein degradation therapies.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential benefits of using topical caffeine products for treating androgenic alopecia but reports no new clinical findings; the authors highlight caffeine's possible positive effects based on existing studies.
February 2016 in “International journal of innovative research in medical science” This study found a statistically significant association between androgenetic alopecia and coronary artery disease in men, with higher grades of alopecia, especially involving the vertex, indicating a greater risk.
24 citations
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January 2013 in “Indian Dermatology Online Journal” This study found that males with androgenetic alopecia had a higher risk of coronary artery disease, with significant differences in several lipid and blood pressure markers compared to controls.
39 citations
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January 2008 in “World Journal of Gastroenterology” This report documents the first known case of acute inflammatory demyelinating polyneuropathy potentially linked to pegylated interferon-alpha 2a in a woman undergoing treatment for chronic hepatitis C.
This review discusses the criteria for evaluating treatments for androgenetic alopecia and emphasizes the importance of shared decision-making, noting no treatment currently meets all desired criteria of efficacy, safety, affordability, and ease of use.
July 2025 in “Journal of Investigative Dermatology” In this study, higher expression of PEDF was observed in hair follicles from balding regions in AGA patients, suggesting that targeting PEDF could be a promising approach for treating androgenetic alopecia.
49 citations
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May 2013 in “JAMA Dermatology” This study found that moderate to severe androgenetic alopecia is an independent predictor of increased mortality risk from diabetes mellitus and heart disease in both sexes.
September 2025 in “Journal of Cutaneous Medicine and Surgery” This expert panel review developed consensus recommendations for managing androgenetic alopecia in Canadian adults, endorsing seven interventions like oral and topical medications and platelet-rich plasma.
May 2026 in “BMC Medicine” This study found that ACOD1 deficiency in dermal papilla cells promotes mitochondrial dysfunction and contributes to cellular senescence in androgenetic alopecia, suggesting ACOD1 as a potential therapeutic target and 4-octyl itaconate as a promising treatment option for AGA.