January 2015 in “Journal of clinical and investigative dermatology” This study found that clipping is the most effective method for anagen synchronization in adult rat models to mimic chemotherapy-induced alopecia, producing robust anagen phases without causing skin trauma.
July 2025 in “Pharmaceuticals” In this study, chitosan nanoparticles loaded with phenobarbital were the most effective in promoting hair regrowth and quality in a mouse model of chemotherapy-induced alopecia, suggesting potential for preventing hair loss in cancer patients.
7 citations
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August 2020 in “Current topics in medicinal chemistry” This review discusses emerging cancer treatment methods focusing on cellular mechanisms unique to cancer cells and concludes no new clinical results.
18 citations
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January 2022 in “Nutrients” This review discusses potential agents, including acetyl-L-carnitine and vitamins, for repurposing in managing chemotherapy-induced peripheral neuropathy and reports no clinical results; the authors emphasize the need for further research.
This scoping review aims to consolidate evidence on the experiences of cancer patients undergoing chemotherapy in oncology facilities across sub-Saharan Africa, highlighting common physical, psychological, and social challenges and identifying under-researched areas for future study.
3 citations
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June 2018 in “The New England Journal of Medicine” This case report describes a 45-year-old woman with persistent fatigue and confusion following hypertension treatment, who developed pulmonary embolism four weeks later.
5 citations
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August 2025 in “Biomedicines” This review highlights the significant impact of cutaneous and oral mucosal adverse events on patients undergoing breast cancer treatment, emphasizing the need for early detection and comprehensive management to maintain treatment adherence and enhance patient care.
June 2025 in “Clinical Cancer Research” In this case report, researchers observed that scalp cooling during chemotherapy with doxorubicin and cyclophosphamide allowed a pregnant breast cancer patient to preserve nearly all her hair, suggesting such treatment may be a safe and effective option for managing chemotherapy-related hair loss during pregnancy.
1 citations
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July 2023 in “Journal of Clinical Medicine” This review provides a detailed overview of the causes, prevalence, pathophysiology, clinical presentation, and treatment of beard alopecia, highlighting conditions such as alopecia areata, pseudofolliculitis barbae, and tinea barbae, and aims to serve as a resource for clinicians handling such cases.
April 2024 in “International journal of molecular sciences” This source reports that for treating keloids and hypertrophic scars, combination pharmacotherapy targeting multiple sites is generally more effective than using a single drug, though outcomes of individual therapies vary and the development of satisfying treatments is ongoing.
31 citations
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March 2017 in “Journal of The American Academy of Dermatology” This study observed various patterns of permanent alopecia in breast cancer patients treated with taxanes and adjuvant hormonal chemotherapy, hypothesizing disruptions in hair follicle cycles due to chemoinflammatory and hormonal factors.
2 citations
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August 2013 in “British Journal of Dermatology” This case report observed a dramatic improvement in a 15-year-old girl's pachyonychia congenita symptoms during chemotherapy for Ewing sarcoma, suggesting chemotherapy's potential role in managing hyperkeratotic conditions.
This study evaluated amphiphilic self-assembling peptides as drug delivery systems and found they effectively ensured prolonged release and therapeutic efficacy for timolol in glaucoma and for chemotherapy agents in cancer treatment, with significant tumor size reduction observed in animal models.
279 citations
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June 1990 in “Journal of Clinical Oncology” The study found that for positive-node breast cancer patients aged 50 and older, adding chemotherapy to tamoxifen significantly improved disease-free survival compared to tamoxifen alone.
27 citations
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January 2018 in “Drug Delivery” In this study, researchers investigated a new local drug delivery system using glycol chitosan hydrogel and doxorubicin (GC10/DOX) for thyroid cancer in mice, finding it produced a stronger antitumor effect compared to conventional treatment methods.
4 citations
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March 2023 in “Current Oncology” This study reviews current methods and emerging approaches to prevent and treat chemotherapy-induced hair loss, reporting that evidence-based research is needed to validate effective strategies, which could enhance cancer patients’ quality of life and treatment compliance.
9 citations
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December 2020 in “Dermatologic Therapy” This review found that oral and topical phosphodiesterase inhibitors and topical prostaglandin analogues are safe and effective treatments for various skin diseases, including psoriasis, atopic dermatitis, vitiligo, and alopecia.
3 citations
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July 2025 in “Current Issues in Molecular Biology” This review discusses how dental pulp stem cells and their derivatives may accelerate skin wound healing by modulating inflammation, promoting angiogenesis, optimizing extracellular matrix structure, and enhancing tissue formation, with implications for translating these findings into therapies for skin and mucosal repair.
46 citations
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April 2021 in “International Journal of Molecular Sciences” This review discusses the potential of curcumin and its formulations to mitigate neuropathic and postoperative pain, highlighting positive outcomes in preclinical and clinical studies but noting the need for further clinical research.
January 2025 in “Dermatology Review” The authors report a rare case of trichilemmal carcinoma in the thigh of a 71-year-old, emphasizing the importance of complete surgical excision to prevent recurrence and support patient prognosis.
4 citations
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January 1989 This paper reviews the principles and challenges of cytotoxic drug therapy in cancer treatment, including effects on normal tissues, drug resistance, administration methods, and the clinical role of chemotherapy, without reporting new experimental results.
June 2026 in “Pharmaceutical Sciences and Research” This prospective observational study in Indonesia found that chemotherapy regimens for lung cancer were 100% in line with treatment guidelines, but adverse effects, including anemia and hair loss, were common among patients, highlighting the need to consider these when optimizing treatment choices.
June 2026 in “Ubaya Repository (University of Surabaya)” In this study, chemotherapy regimens for lung cancer in Indonesian patients were found to be guideline-congruent, but adverse effects like anemia and hair loss were common, suggesting a need for managing these to optimize treatment.
1 citations
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May 2023 in “Jurnal Kedokteran Diponegoro” This study examined the most common chemotherapy side effects among patients with prostate, bladder, and testicular cancer, noting hair loss, fatigue, and decreased appetite as frequent symptoms.
1 citations
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December 2022 in “Jurnal Riset Kesehatan” This study found that family actions such as preparing preferred foods and managing routines helped cancer patients manage chemotherapy side effects at home.
December 2023 in “Malahayati International Journal of Nursing and Health Science” In this study, researchers at the "Estella" Children's Cancer Center observed that 80.5% of children experience hair loss, and most parents reported nausea, vomiting, and mood swings as the most disruptive effects of chemotherapy during pediatric cancer treatment.
This study reports that FDA-approved scalp cooling caps, like DigniCap and Paxman, can help 50-66% of breast cancer patients retain at least 50% of their hair during chemotherapy, with specific recommendations and limitations discussed for different patient groups.
2 citations
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January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This article presents two cases of anagen effluvium following oral albendazole use and summarizes previously reported cases, suggesting this side effect may occur with this drug.
This study describes various actions taken by parents to manage the side effects of chemotherapy in children with leukemia, highlighting a range of strategies from dietary adjustments to topical treatments.
August 2023 in “Institutional Repositories DataBase (IRDB)” This research explored the impact of anticancer drugs on the scalp and found significant differences in scalp texture and features associated with alopecia, suggesting potential for assessing scalp morphology and changes during the hair regrowth process through image analysis.