153 citations,
November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
150 citations,
February 2013 in “Surgical Infections” Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.
140 citations,
August 2011 in “Biomaterials” Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
134 citations,
December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
122 citations,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
116 citations,
December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
113 citations,
March 2018 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
112 citations,
October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
95 citations,
November 2018 in “Australasian journal of dermatology” Alopecia areata treatment varies, with no optimal method established yet.
95 citations,
February 2018 in “Dermatology and Therapy” Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
89 citations,
January 2013 in “Acta dermato-venereologica” The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
83 citations,
March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
81 citations,
July 2012 in “Translational Psychiatry” Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
78 citations,
September 2006 in “International Journal of Cosmetic Science” Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
77 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
76 citations,
December 2009 in “Clinics in Dermatology” Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
76 citations,
July 2006 in “Veterinary Dermatology” Imiquimod 5% cream reduced equine sarcoids in most cases.
73 citations,
April 1999 in “Dermatologic Clinics” Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.
68 citations,
May 2021 in “Endocrine” People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
68 citations,
September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
68 citations,
September 2003 in “British Journal of Dermatology” Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
67 citations,
October 1997 in “Dermatologic Surgery” The EpiLight Hair Removal System removed about 60% of hair with some side effects, and more research is needed to confirm long-term effectiveness.
66 citations,
March 2009 in “British journal of surgery” Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
63 citations,
January 2012 in “The European Journal of Contraception & Reproductive Health Care” Some birth control pills have a higher risk of blood clots than others.
60 citations,
December 2015 in “Lasers in Medical Science” Low-level laser therapy is safe and can increase hair growth for male and female pattern hair loss.
60 citations,
December 1998 in “Clinical Pharmacology & Therapeutics” Both drugs lower DHT levels, with GI198745 being more effective.
59 citations,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.