15 citations
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October 2016 in “Journal of The European Academy of Dermatology and Venereology” This meta-analysis found that patients with androgenetic alopecia have significantly abnormal lipid profiles, which could contribute to the link between this condition and cardiovascular diseases.
18 citations
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July 2019 in “Clinical Endocrinology” The researchers reported that among Mediterranean Sicilian women with PCOS, Phenotype B exhibited the most severe metabolic abnormalities, notably obesity and altered glucose metabolism, whereas Phenotype D showed no such issues.
May 2024 in “Journal of cosmetic dermatology” In this retrospective study, oral tofacitinib treatment for at least 6 months improved scalp hair loss in 69.1% of alopecia areata patients, with patchy AA cases responding better compared to other subtypes, and no significant adverse effects were reported.
April 2018 in “Journal of Investigative Dermatology” This study found that sensitive scalp is characterized by increased pH levels, redness, altered sebum composition, and a disrupted microbiome, suggesting these features could inform treatment approaches.
July 2019 in “International journal of contemporary medical research” This study found that dyslipidemia was more common in male patients with androgenetic alopecia than in controls, particularly among those with severe AGA, suggesting a higher risk of altered serum lipids.
June 2023 in “Journal of biological chemistry/The Journal of biological chemistry” This study on Sdr16c5/Sdr16c6-null mice found that inactivating these genes significantly increased Meibomian gland secretions and altered lipid profiles but had a subtle impact on sebogenesis, suggesting the genes control a bifurcation point in meibogenesis pathways.
March 2025 in “Journal of Pakistan Association of Dermatologists” This study observed that 62.7% of men with androgenetic alopecia had abnormal blood lipid levels, suggesting the importance of assessing lipid profiles in these individuals for early detection of cardiovascular and metabolic risks.
24 citations
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November 2023 in “NEWPORT INTERNATIONAL JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES” This article reviews the various short- and long-term side effects of antiretroviral therapy for HIV, highlighting issues like dyslipidemia and hypertension, but reports no new clinical results.
October 2025 in “Diseases” The researchers suggest that inflammation could be a key mechanism in the development of long COVID, potentially causing symptoms that emerge months after the acute phase of the disease resolves.
June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
March 2020 in “Journal of the turkish academy of dermatology” In this study, no significant difference was found in serum triglyceride and HDL cholesterol levels between male patients with androgenetic alopecia and those without.
March 2025 in “Journal of Endocrinology and Metabolism” This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.
April 2017 in “Journal of Investigative Dermatology” This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.
91 citations
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July 2022 in “Frontiers in Endocrinology” This study reported that Chinese women with PCOS exhibited diverse lipid profiles based on different characteristics, which may help understand their increased risk of cardiovascular disease.
5 citations
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June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” This study found that women with polycystic ovary syndrome have higher triglyceride and fasting glucose levels in obese individuals and higher total cholesterol levels in non-obese individuals compared to healthy women.
January 2021 in “Menoufia Medical Journal” This study found that patients with early-onset androgenetic alopecia had significantly higher levels of fasting blood sugar, triglycerides, and cholesterol, suggesting an increased risk of developing coronary artery disease.
9 citations
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May 2015 in “Cardiology Clinics” This review discusses the timing and management of dyslipidemia screening around pregnancy and emphasizes dietary, exercise, and glycemic interventions during pregnancy without reporting new clinical outcomes.
April 2025 in “Journal of Cosmetic Dermatology” This study suggests potential causal associations between certain lipid levels, specifically HDL-C and triglycerides, and alopecia areata, highlighting the importance of lipid management as a therapeutic target.
4 citations
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June 2021 in “Applied Sciences” This study found that women with PCOS had higher body fat and worse insulin resistance than non-PCOS women, with body composition influencing metabolic profiles independently of PCOS status.
June 2023 in “Frontiers in Genetics” This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.
This study found that in men with androgenetic alopecia, elevated triglycerides were the only factor consistently associated with the condition, suggesting a potential link between AGA and lipid metabolism, although other hormonal, metabolic, and sleep factors were not significantly different after propensity score matching.
June 2017 in “Journal of The European Academy of Dermatology and Venereology” This meta-analysis found that patients with androgenetic alopecia have an atherogenic lipid profile, with higher LDL, triglycerides, and total cholesterol, and lower HDL, potentially explaining increased cardiovascular risk.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” This study reports a solid causal relationship between increased serum levels of ApoB, LDL, and VLDL and an elevated risk of androgenic alopecia.
25 citations
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July 2019 in “Experimental Dermatology” This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.
14 citations
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October 2018 in “PloS one” In this study, Far2-/- mice were observed to develop focal alopecia with altered sebaceous gland morphology and lower skin lipid levels compared to wildtype mice.
26 citations
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January 2000 in “Hormone research in paediatrics” This review discusses the relationship between hyperandrogenism and insulin resistance in PCOS, focusing on insulin dynamics, molecular mechanisms, genetic studies, and potential long-term treatments, but presents no new clinical results.
November 2025 in “Frontiers in Pharmacology” In this study, XZYFD, a Traditional Chinese Medicine formulation, was found to improve androgenetic alopecia in a testosterone-induced mouse model by promoting hair regrowth, restoring follicular morphology, and modulating androgen metabolism, MAPK signaling, and lipid metabolism pathways, suggesting potential benefits for patients with metabolic dysfunction.
34 citations
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January 2014 in “Indian Dermatology Online Journal” This study supports evaluating metabolic syndrome and insulin resistance in young males with advanced androgenic alopecia to potentially reduce future cardiovascular and type 2 diabetes risks.
1 citations
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January 2001 in “Drug and therapeutics bulletin” This review discusses the management of polycystic ovary syndrome in women and reports no new clinical results.
February 2019 in “Journal of Pakistan Association of Dermatology” This study found that abnormal serum lipid levels were prevalent among male patients with androgenetic alopecia, with high triglycerides and low HDL observed frequently.