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The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Endocrine diseases in children often cause skin changes like dryness, redness, acne, hair loss, and more.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

SkQ1 antioxidant improved health and lifespan in mice.

Healthy scalp reduces hair loss by managing oxidative stress.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

COX-2 levels change during the hair cycle and affect skin and hair growth.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Sensitive scalp has higher pH, more redness, abnormal sebum, and altered bacterial makeup.

Teens with PCOS and a mom with PCOS have higher insulin resistance and lower adiponectin levels, which could signal early metabolic problems.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Metabolic syndrome can cause serious health issues and should be considered when treating women with severe acne.

High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.

MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.

Premature graying of hair is linked to vitamin D and B12 deficiencies, thyroid issues, iron imbalance, stress, and lifestyle habits, and affects quality of life.

Low Vitamin D, Vitamin B12, and iron levels, as well as thyroid issues, are strongly linked to premature greying of hair, which also negatively affects quality of life.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

A man's severe skin reaction from cancer treatment improved with early diagnosis and proper medication.

People with male pattern baldness are more likely to have metabolic syndrome.

Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.