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The document concludes that specific hair and blood vessel abnormalities in infants with seizures and developmental issues may indicate Menkes disease, which lacks a cure and is often fatal by age 3.

Treatment during development affects hormone balance and sexual behavior in male rats.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

An 11-month-old boy with Menkes disease had severe brain shrinkage and abnormal blood vessels, and didn't respond well to treatment.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

Skin health and diseases are closely linked to metabolic processes.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Researchers found a new ABCD1 gene mutation linked to a rare brain and nerve disorder with unusual brain changes.

Vegetarians should take B vitamin supplements to avoid health issues.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

PCOS may increase the risk of mental health issues like depression and anxiety.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.