November 2024 in “SKIN The Journal of Cutaneous Medicine” In this study, NH Asian alopecia areata patients reported the highest levels of severe disease, with NH White patients having the most eyebrow involvement and Hispanic patients showing the least severity.
December 2025 in “Egyptian Reviews for Medical and Health Sciences .” This study found that, among patients in Ismailia, Egypt, patchy alopecia areata was the most common form, with a significant positive correlation between the number of lesions and disease severity, and noted males predominantly affected by this condition.
December 2013 in “International Journal of Dermatology” The clinical signs of Adams-Oliver syndrome can vary greatly, even among family members.
1 citations
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September 2023 in “Journal of the American Academy of Dermatology” This abstract introduces baricitinib as an approved treatment for adults with severe alopecia areata in the US, Europe, and Japan, but does not report any specific study results or findings.
24 citations
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May 2006 in “Journal of Investigative Dermatology” This study found that allergen treatment in alopecia areata mice appeared to alter leukocyte subset distribution and impaired dendritic cell migration, which may affect T-cell activation and hair follicle recovery.
6 citations
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July 2022 in “Journal of health economics and outcomes research” This study found that US adolescents with alopecia areata, especially those with alopecia totalis or universalis, experience significantly higher healthcare costs and resource use compared to matched controls.
9 citations
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April 2023 in “Experimental Dermatology” This study found that adding allergen immunotherapy to conventional treatment may reduce relapse-related hair loss in house dust mite-allergic alopecia areata patients over a 3-year period.
1 citations
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April 2019 in “Acta Medica Philippina” This review discusses emerging evidence on azathioprine's efficacy and safety for severe alopecia areata, reporting sustained response in many patients but emphasizing the need for controlled trials.
February 2026 in “Frontiers in Public Health” This study identified that while the overall burden of AA among adolescents and young adults globally continues to rise, the age-standardized rates have slightly decreased, with notable disparities across age, gender, region, and socioeconomic status.
January 2023 in “Pharmaceutics” In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.
January 2026 in “Frontiers in Medicine” This review identified evidence gaps in NHIRD, emphasizing the lack of validated diagnostic criteria and the need for further research on ocular and systemic comorbidities associated with AA to enhance patient care and treatment strategies.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this study, UPA at doses of 15 mg and 30 mg showed higher efficacy than placebo for treating severe alopecia areata in adults and adolescents over 24 weeks, with a safety profile similar to approved uses.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review compiles current insights into alopecia areata's epidemiology, immune mechanisms, diagnosis, treatment options, including novel JAK inhibitors, and its severe psychosocial impact, while also highlighting emerging research areas.
29 citations
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May 2016 in “Journal of the American Academy of Dermatology” This study observed that patients with alopecia areata had decreased odds of developing stroke and a potential decreased risk of acute myocardial infarction, though the latter was not statistically significant.
June 2023 in “International Journal of Research in Dermatology” This study observed a high prevalence of severe markers among pediatric alopecia areata patients, identifying AA subtotalis as more frequent, with nail changes and various hair markers suggesting progression to severe forms.
July 2026 in “SKIN The Journal of Cutaneous Medicine” This case report details a 17-year-old male with Alopecic and Aseptic Nodules of the Scalp successfully treated with doxycycline and intralesional corticosteroids, highlighting the importance of thorough evaluation for accurate diagnosis.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Abatacept may help some people with alopecia areata regrow hair.
This study found a significant positive association between higher air quality index values and the incidence of alopecia areata, with a clear dose-response relationship observed among the participants.
November 2023 in “Research Portal Denmark” This review highlights the variability and unpredictability of alopecia areata, ranging from single scalp patches to total body hair loss, and notes the 2022 approval of the first AA-specific drug, baricitinib, potentially spurring new research into targeted treatments.
8 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses recent advancements made in using mouse models to investigate the genetic complexity and pathogenesis of alopecia areata, emphasizing potential new treatment targets, but it reports no new findings.
33 citations
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December 2005 in “Archives of dermatology” This study presents case reports of four patients with alopecia areata or alopecia universalis, highlighting varied responses to treatments like prednisone, intralesional triamcinolone, and squaric acid dibutyl ester.
July 2022 in “Media Dermato Venereologica Indonesiana” In this case study, a 29-year-old man with alopecia areata experienced satisfactory hair regrowth after five months of combined intralesional triamcinolone acetonide and platelet-rich plasma therapy.
6 citations
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August 2022 in “International Journal of Molecular Sciences” This review summarizes the role of Ectodysplasin A signaling in skin appendage development and various diseases, noting potential clinical applications but reporting no new research findings.
September 2024 in “Journal of the American Academy of Dermatology” In this retrospective case-control study, researchers reported that patients with alopecia areata had significantly increased odds of venous thromboembolism compared to matched controls, suggesting a potential association between alopecia areata and risk of VTE.
April 2018 in “Journal of Investigative Dermatology” This study found that high skin expression of amphiregulin in acute graft-versus-host disease was associated with severe disease grade, poor overall survival, and increased non-relapse mortality.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This study suggests that congenital alopecia areata should be considered for newborns with alopecia, supporting the use of topical corticosteroids as a reasonable initial treatment option based on observed regrowth.
1 citations
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March 2025 in “Pediatric Dermatology” This review highlights the evolution of assessment tools for alopecia areata, revealing newer tools that evaluate beyond scalp hair loss, including psychosocial impact and disease chronicity, which can aid clinicians in developing individualized treatment strategies and enhance research in pediatric dermatology.
December 2023 in “EPRA international journal of multidisciplinary research” In this review, researchers examined current knowledge on alopecia areata, finding it affects approximately 2% of individuals, with a likely autoimmune and genetic basis, and highlighting its association with other medical and psychiatric conditions, although no cure currently exists.
April 2024 in “Research Square” This study observed that children with alopecia areata had higher anxiety and depression scores, and their families showed more neglectful parenting styles compared to healthy controls.
May 2017 in “Journal of The American Academy of Dermatology” This study reported an increase in allergic contact dermatitis cases linked to natural products, particularly propolis and marigold, with a higher incidence in women than men.