Race and Ethnicity Sub-Groups of Alopecia Areata Patients Have Differing Clinical Characteristics: TARGET-DERM AA

    Maria Hordinsky, Claire Bristow, Sven Richter, Ahmed M. Soliman, Keith Knapp, Breda Muñoz, Julie M. Crawford, Amy S. Paller, Stephan Chapman, Lara Wine Lee, Natasha Atanaskova Mesinkovska, Benjamin Ungar
    TLDR Alopecia areata severity and symptoms vary by race and ethnicity.
    The study "Race and Ethnicity Sub-Groups of Alopecia Areata Patients have Differing Clinical Characteristics: TARGET-DERM AA" analyzed 267 alopecia areata (AA) patients from the United States and Canada, focusing on racial and ethnic differences in disease severity and characteristics. The cohort consisted of 61.4% females, with 53.2% adults, and included 28.5% Hispanic, 52.1% Non-Hispanic (NH) White, 8.6% NH Black, and 6.4% NH Asian participants. NH Asian patients had the highest proportion of severe disease (SALT>50) at 47.1%, followed by NH Black (34.8%), NH White (31.7%), and Hispanic (19.7%) patients. Eyebrow involvement was most prevalent in NH Whites (44.6%), while eyelash involvement was highest in NH Black patients (39.1%). The study highlights significant differences in AA severity and characteristics across racial and ethnic groups, with NH Asian patients experiencing the most severe disease. Further research is needed to understand the impact of AA on non-White patients' quality of life.
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