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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Keratin mutations cause skin diseases and could lead to new treatments.

Selective breeding can enhance immunity in dairy cattle.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Genetic variants affect minoxidil hair loss treatment success.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Certain gene variations increase male hair loss risk, influenced by hormone levels.

Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

UV photography can help identify people at higher risk for skin cancer, and male pattern baldness at age 45 is linked to a higher risk of certain skin cancers.

Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.

Men who start balding at age 20 may have a higher chance of getting aggressive prostate cancer.

The patient with total hair loss did not regrow hair despite treatment, indicating a poor outlook for this type of hair loss.

Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Lamins are vital for cell survival, organ development, and preventing premature aging.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Explosions don't stop hair proteins from being used to identify people.

BMP signaling is essential for the development of touch domes.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.