research A Practical Approach to the Diagnosis and Management of Hair Loss in Children and Adolescents
Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.
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research A Splice Variant in KRT71 Is Associated with Curly Coat Phenotype of Selkirk Rex Cats
A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
research A Detective Look at Hair Biopsies from African-American Patients
Recognizing specific features of African-American hair can help diagnose hair loss conditions.
research Trilostane Treatment of a Dog with Functional Adrenocortical Neoplasia
Trilostane helped a dog with an adrenal tumor feel better and stay healthy.
research Improvement in the Inflammatory Aspect of Androgenetic Alopecia: A Pilot Study with an Antimicrobial Lotion
Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.
research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque
Taking finasteride pills and using minoxidil lotion together can help grow hair.
research Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients
Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.
research Novel De Novo Pathogenic Variant in the ODC1 Gene in a Girl with Developmental Delay, Alopecia, and Dysmorphic Features
A 32-month-old Caucasian female was identified with a heterozygous de novo nonsense mutation in the ODC1 gene, leading to a new pediatric disorder characterized by developmental delay, alopecia, and other symptoms such as macrosomia and macrocephaly. This mutation resulted in elevated ODC protein and polyamine levels in red blood cells. The case confirmed similar symptoms observed in a transgenic ODC1 mouse model. The mutation was identified through whole-exome sequencing and confirmed by Sanger sequencing. The patient might benefit from treatment with α-difluoromethylornithine, an FDA-approved drug.
research A Cell-Based System for Screening Hair Growth-Promoting Agents
Apigenin may help promote hair growth and could treat hair loss.
research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
research A Primer for Studying Cell Cycle Dynamics of the Human Hair Follicle
The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
research More About X-Linked Testicular Feminization of the Mouse as a Noninducible (is) Mutation of a Regulatory Locus: 5α-Androstan-3α-17β-Diol as the True Inducer of Kidney Alcohol Dehydrogenase and β-Glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research Treatment of Telogen Effluvium Using a Dietary Supplement Containing Boswellia Serrata, Curcuma Longa, and Vitis Vinifera: Results of an Observational Study
A dietary supplement with Boswellia serrata, Curcuma longa, and Vitis vinifera showed potential improvement in hair health for telogen effluvium patients, but more research is needed.
research A Kindred With Mutant IKAROS and Autoimmunity
A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.
research Topical Valproic Acid Increases Hair Count in Male Patients with Androgenetic Alopecia: A Randomized, Comparative, Clinical Feasibility Study Using Phototrichogram Analysis
Valproic acid increases hair count in men with hair loss.
research Epidemiology of Hirsutism Among Women of Reproductive Age in the Community: A Simplified Scoring System
A simplified scoring system can effectively diagnose hirsutism in Chinese women of reproductive age.
research Hereditary Vitamin D-Resistant Rickets (HVDRR) Owing to a Heterozygous Mutation in the Vitamin D Receptor
A girl had rickets due to a gene mutation affecting vitamin D response.
research A Comparative Study of Dyslipidemia in Men and Women with Androgenic Alopecia
People with early onset baldness have higher bad cholesterol and lower good cholesterol, increasing their heart disease risk.
research Toxic Hepatitis Induced by Shou-Wu-Pian, a Chinese Herbal Preparation
A woman's liver was damaged by taking the herbal supplement Shou-Wu-Pian, but it got better after she stopped using it.
research A Review on the Treatment of Acne Vulgaris
Choose acne treatments based on appearance, lesion type, severity, scarring, and mental impact.
research Cushing's Syndrome Due to Pharmacological Interaction in a Cystic Fibrosis Patient
A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.
research Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study
Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.
research A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice
A special stem cell fluid can speed up wound healing and hair growth in mice.
research Aromatase Deficiency in a Male Patient: Case Report and Literature Review
A male with aromatase deficiency improved bone health with estradiol treatment.
research A Pilot Study for Triple Combination Therapy with a Low-Fluence 1064 nm Q-Switched Nd:YAG Laser, Hydroquinone Cream, and Oral Tranexamic Acid for Recalcitrant Riehl’s Melanosis
The combination therapy significantly improved Riehl’s melanosis in patients without serious side effects.
research Early Onset and Novel Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat
A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.
research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine
A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
research A Review of Scalp Camouflaging Agents and Prostheses for Individuals with Hair Loss
Using wigs, hairpieces, and sprays can help people with hair loss feel better about themselves.
research A Distinct Gene Close to the Hairless Locus on Chromosome 8p Underlies Hereditary Marie Unna Type Hypotrichosis in a German Family
A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.
research Ichthyosis Follicularis with Alopecia and Photophobia in a Mother and Daughter
A mother and daughter had severe skin, hair, and eye issues linked to IFAP.